Desmoid tumors: a comprehensive review

M Bektas, T Bell, S Khan, B Tumminello… - Advances in …, 2023 - Springer
Desmoid tumors (DT) are rare, locally aggressive, fibroblastic soft-tissue tumors that are
characterized by infiltrative growth and can affect organs and adjacent structures, resulting …

Evolving strategies for management of desmoid tumor

RF Riedel, M Agulnik - Cancer, 2022 - Wiley Online Library
Desmoid tumors (DTs) are rare soft tissue mesenchymal neoplasms that may be associated
with impairments, disfigurement, morbidity, and (rarely) mortality. DT disease course can be …

[HTML][HTML] Targeted and immuno-based therapies in sarcoma: mechanisms and advances in clinical trials

F Tang, Y Tie, YQ Wei, CQ Tu, XW Wei - Biochimica et Biophysica Acta …, 2021 - Elsevier
Sarcomas represent a distinct group of rare malignant tumors with high heterogeneity.
Limited options with clinical efficacy for the metastatic or local advanced sarcoma existed …

Desmoid-type fibromatosis: Current therapeutic strategies and future perspectives

R Ibrahim, T Assi, R Khoury, C Ngo, M Faron… - Cancer Treatment …, 2024 - Elsevier
Desmoid tumors (DT) are rare, slow-growing, locally invasive soft tissue tumors that often
pose significant therapeutic challenges. Traditional management strategies including active …

New strategies in soft tissue sarcoma treatment

M Spalato-Ceruso, NE Ghazzi, A Italiano - Journal of Hematology & …, 2024 - Springer
Soft tissue sarcomas (STS) have long been a formidable challenge in oncology, partly
because of their rarity and diversity, which complicates large-scale studies and slows the …

Systemic Chemotherapies Retain Antitumor Activity in Desmoid Tumors Independent of Specific Mutations in CTNNB1 or APC: A Multi-institutional Retrospective …

MJ Nathenson, J Hu, R Ratan, N Somaiah, R Hsu… - Clinical Cancer …, 2022 - AACR
Purpose: Determine whether specific CTNNB1 or APC mutations in patients with desmoid
tumor were associated with differences in clinical responses to systemic treatments …

The Notch signaling pathway in desmoid tumor: recent advances and the therapeutic prospects

C Zheng, J Huang, G Xu, W Li, X Weng… - Biochimica et Biophysica …, 2024 - Elsevier
Desmoid tumor (DT) is a rare fibroblastic soft-tissue neoplasm that is characterized by local
aggressiveness but no metastatic potential. Although the prognosis is relatively favorable …

Sporadic desmoid tumours: systematic review with reflection on the role of cryoablation

RL Cazzato, J Gantzer, P de Marini, J Garnon… - Cardiovascular and …, 2022 - Springer
Desmoid tumours (DT) are rare locally infiltrative soft-tissue tumours which do not
metastasise. DT arise sporadically or are associated with familial syndromes, with different …

Current chemoprevention approaches in Lynch syndrome and familial adenomatous polyposis: a global clinical practice survey

KA Mraz, R Hodan, L Rodgers-Fouche, S Arora… - Frontiers in …, 2023 - frontiersin.org
Background International chemoprevention preferences and approaches in Lynch
syndrome (LS) and APC-associated polyposis, including Familial adenomatous polyposis …

A clinician's perspective on the new organ mesentery and non-vascular mesenteropathies

M Ahmed - Frontiers in Physiology, 2024 - frontiersin.org
Mesentery was discovered as a new organ in 2017. It is a continuous membranous tissue
from the duodenojejunal flexure to the anorectal junction. It has distinct anatomy, physiology …