The changing therapeutic landscape of head and neck cancer

JD Cramer, B Burtness, QT Le, RL Ferris - Nature reviews Clinical …, 2019 - nature.com
Head and neck cancers are a heterogeneous collection of malignancies of the upper
aerodigestive tract, salivary glands and thyroid. In this Review, we primarily focus on the …

Head and neck cancer

LQM Chow - New England Journal of Medicine, 2020 - Mass Medical Soc
Head and Neck Cancer Most head and neck cancers (73% in the United States) are now
related to human papillomavirus infection rather than tobacco and alcohol. Primary cancers …

NCCN Guidelines® insights: Head and neck cancers, version 1.2022: Featured updates to the NCCN guidelines

JJ Caudell, ML Gillison, E Maghami, S Spencer… - Journal of the National …, 2022 - jnccn.org
The NCCN Guidelines for Head and Neck Cancers address tumors arising in the oral cavity
(including mucosal lip), pharynx, larynx, and paranasal sinuses. Occult primary cancer …

Phase II randomized trial of transoral surgery and low-dose intensity modulated radiation therapy in resectable p16+ locally advanced oropharynx cancer: an ECOG …

RL Ferris, Y Flamand, GS Weinstein, S Li… - Journal of clinical …, 2022 - ascopubs.org
PURPOSE Definitive or postoperative chemoradiation (CRT) is curative for human
papillomavirus–associated (HPV+) oropharynx cancer (OPC) but induces significant toxicity …

Treating head and neck cancer in the age of immunotherapy: a 2023 update

A Bhatia, B Burtness - Drugs, 2023 - Springer
Most patients diagnosed with head and neck squamous cell carcinoma (HNSCC) will
present with locally advanced disease, requiring multimodality therapy. While this approach …

Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma

RL Ferris, W Westra - Annual Review of Pathology: Mechanisms …, 2023 - annualreviews.org
Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV-OPSCC)
has one of the most rapidly increasing incidences of any cancer in high-income countries …

Comprehensive review of surgical microscopes: technology development and medical applications

L Ma, B Fei - Journal of biomedical optics, 2021 - spiedigitallibrary.org
Significance: Surgical microscopes provide adjustable magnification, bright illumination, and
clear visualization of the surgical field and have been increasingly used in operating rooms …

Deintensification candidate subgroups in human papillomavirus–related oropharyngeal cancer according to minimal risk of distant metastasis

B O'Sullivan, SH Huang, LL Siu, J Waldron… - Journal of clinical …, 2013 - ascopubs.org
Purpose To define human papillomavirus (HPV)–positive oropharyngeal cancers (OPC)
suitable for treatment deintensification according to low risk of distant metastasis (DM) …

Diagnosis and management of squamous cell carcinoma of unknown primary in the head and neck: ASCO guideline

E Maghami, N Ismaila, A Alvarez… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE To provide evidence-based recommendations to practicing physicians and other
health care providers on the diagnosis and management of squamous cell carcinoma of …

[HTML][HTML] De-escalation treatment protocols for human papillomavirus-associated oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis of …

L Masterson, D Moualed, ZW Liu, JEF Howard… - European journal of …, 2014 - Elsevier
Iatrogenic complications associated with current treatment protocols for oropharyngeal
squamous cell carcinoma are noted to cause high rates of acute and chronic morbidity. The …