Exploring structural diversity of microbe secondary metabolites using OSMAC strategy: A literature review

R Pan, X Bai, J Chen, H Zhang, H Wang - Frontiers in Microbiology, 2019 - frontiersin.org
Microbial secondary metabolites (MSMs) have played and continue to play a highly
significant role in the drug discovery and development process. Genetically, MSM chemical …

Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural Product …, 2016 - pubs.rsc.org
Covering: 2014. Previous review: Nat. Prod. Rep., 2015, 32, 116–211 This review covers the
literature published in 2014 for marine natural products (MNPs), with 1116 citations (753 for …

Cryptic metabolites from marine-derived microorganisms using OSMAC and epigenetic approaches

C Pinedo-Rivilla, J Aleu, R Durán-Patrón - Marine Drugs, 2022 - mdpi.com
Marine microorganisms have proven to be a source of new natural products with a wide
spectrum of biological activities relevant in different industrial sectors. The ever-increasing …

[PDF][PDF] Natural product reports

JW Blunt, BR Copp, RA Keyzers, MH Munroa… - Nat Prod Rep, 2016 - academia.edu
This review covers the literature published in 2015 for marine natural products (MNPs), with
1220 citations (792 for the period January to December 2015) referring to compounds …

Advances in Antarctic research for antimicrobial discovery: a comprehensive narrative review of bacteria from Antarctic environments as potential sources of novel …

K Núñez-Montero, L Barrientos - Antibiotics, 2018 - mdpi.com
The recent emergence of antibiotic-resistant bacteria has become a critical public health
problem. It is also a concern for industries, since multidrug-resistant microorganisms affect …

Insights into fungal diversity of a shallow-water hydrothermal vent field at Kueishan Island, Taiwan by culture-based and metabarcoding analyses

KL Pang, SY Guo, IA Chen, G Burgaud, ZH Luo… - PLoS …, 2019 - journals.plos.org
This paper reports the diversity of fungi associated with substrates collected at a shallow
hydrothermal vent field at Kueishan Island, Taiwan, using both culture-based and …

[HTML][HTML] Stress-driven discovery in the natural products: A gateway towards new drugs

SS ul Hassan, H Jin, T Abu-Izneid, A Rauf… - Biomedicine & …, 2019 - Elsevier
Elicitation by chemical means including heavy metals is one of a novel technique for drug
discoveries. In this review, the effect of heavy metals on animal, plants and microorganisms …

Stress-Driven Discovery of New Angucycline-Type Antibiotics from a Marine Streptomyces pratensis NA-ZhouS1

N Akhter, Y Liu, BN Auckloo, Y Shi, K Wang, J Chen… - Marine Drugs, 2018 - mdpi.com
Natural products from marine actinomycetes remain an important resource for drug
discovery, many of which are produced by the genus, Streptomyces. However, in standard …

Extremophilic fungi from marine environments: underexplored sources of antitumor, anti-infective and other biologically active agents

LA Giddings, DJ Newman - Marine drugs, 2022 - mdpi.com
Marine environments are underexplored terrains containing fungi that produce a diversity of
natural products given unique environmental pressures and nutrients. While bacteria are …

New compounds from a hydrothermal vent crab-associated fungus Aspergillus versicolor XZ-4

C Pan, Y Shi, X Chen, CTA Chen, X Tao… - Organic & Biomolecular …, 2017 - pubs.rsc.org
Three new quinazoline derivatives (1–3), one new oxepin-containing natural product (4) and
four new cyclopenin derivatives (5–7 and 9) have been isolated from an EtOAc extract of the …