The prevalence of type 2 diabetes mellitus is increasing in both sexes, but men are usually
diagnosed at a younger age and lower body fat mass than women. Worldwide, an estimated …

Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

High levels of cholesterol are generally considered to be associated with atherosclerosis. In
the past two decades, however, a number of studies have shown that excess cholesterol …

In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Osteoporosis is a pathological condition characterized by an accelerated bone resorption
rate, resulting in decreased bone density and increased susceptibility to fractures …

Hyperlipidemia negatively affects osteogenesis, thereby impairing bone healing. However,
few biomaterials have been developed for bone tissue engineering to solve this problem …

Osteoporosis is a common systemic metabolic disease characterized by a decrease in bone
density and bone mass, destruction of bone tissue microstructure, and increased bone …

The aim of the present review is to discuss the roles of vitamin K (phylloquinone or
menaquinones) and vitamin K-dependent proteins, and the combined action of the vitamins …

An extensive evaluation of disease occurrence after statin use based on a “hypothesis-free”
approach remains scarce. To examine the effect of statin use on the potential risk of …

Background Combining mouse experiments with big data analysis of the Austrian
population, we investigated the association between high-dose statin treatment and bone …