[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation

CA Labarrere, GS Kassab - Frontiers in Nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

SARS-CoV-2 inhibits NRF2-mediated antioxidant responses in airway epithelial cells and in the lung of a murine model of infection

Y Qu, A Haas de Mello, DR Morris… - Microbiology …, 2023 - Am Soc Microbiol
Several viruses have been shown to modulate the transcription factor nuclear factor
erythroid 2-related factor 2 (NRF2), the master regulator of redox homeostasis. The severe …

[HTML][HTML] Glutathione deficiency in the pathogenesis of SARS-CoV-2 infection and its effects upon the host immune response in severe COVID-19 disease

CA Labarrere, GS Kassab - Frontiers in Microbiology, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus
disease 19 (COVID-19) has numerous risk factors leading to severe disease with high …

Autoantibodies-enemies, and/or potential allies?

H Ma, C Murphy, CE Loscher… - Frontiers in Immunology, 2022 - frontiersin.org
Autoantibodies are well known as potentially highly harmful antibodies which attack the host
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …

COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches

S Kakavandi, B Hajikhani, P Azizi, F Aziziyan… - Cell Communication and …, 2024 - Springer
Extensive research in countries with high sociodemographic indices (SDIs) to date has
shown that coronavirus disease 2019 (COVID-19) may be directly associated with more …

Role of innate and adaptive cytokines in the survival of COVID-19 patients

J Monserrat, A Gómez-Lahoz, MA Ortega… - International journal of …, 2022 - mdpi.com
SARS-CoV-2 is a new coronavirus characterized by a high infection and transmission
capacity. A significant number of patients develop inadequate immune responses that …

[PDF][PDF] Vimentin is an important ACE2 co-receptor for SARS-CoV-2 in epithelial cells

J Arrindell, P Abou Atmeh, L Jayet, Y Sereme, JL Mege… - IScience, 2022 - cell.com
Vimentin is a type III intermediate filament protein, widely expressed in mesenchymal cells.
Mainly located in the cytoplasm, vimentin can also appear at extracellular locations, where it …

Coordinated innate and T-cell immune responses in mild COVID-19 patients from household contacts of COVID-19 cases during the first pandemic wave

A Aiello, A Grossi, S Meschi, M Meledandri… - Frontiers in …, 2022 - frontiersin.org
Objective To better define the immunopathogenesis of COVID-19, the present study aims to
characterize the early immune responses to SARS-CoV-2 infection in household contacts of …

[HTML][HTML] Innate lymphoid cell plasticity in mucosal infections

AA Korchagina, E Koroleva, AV Tumanov - Microorganisms, 2023 - mdpi.com
Mucosal tissue homeostasis is a dynamic process that involves multiple mechanisms
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …