Sensitivity enhancement in solution NMR: Emerging ideas and new frontiers

JH Lee, Y Okuno, S Cavagnero - Journal of magnetic resonance, 2014 - Elsevier
Modern NMR spectroscopy has reached an unprecedented level of sophistication in the
determination of biomolecular structure and dynamics at atomic resolution in liquids …

Practical dissolution dynamic nuclear polarization

SJ Elliott, Q Stern, M Ceillier, T El Daraï… - Progress in Nuclear …, 2021 - Elsevier
This review article intends to provide insightful advice for dissolution-dynamic nuclear
polarization in the form of a practical handbook. The goal is to aid research groups to …

Hyperpolarized magnetic resonance as a sensitive detector of metabolic function

A Comment, ME Merritt - Biochemistry, 2014 - ACS Publications
Hyperpolarized magnetic resonance allows for noninvasive measurements of biochemical
reactions in vivo. Although this technique provides a unique tool for assaying enzymatic …

Ultrafast 2D NMR for the analysis of complex mixtures

C Lhoste, B Lorandel, C Praud, A Marchand… - Progress in Nuclear …, 2022 - Elsevier
Abstract 2D NMR is extensively used in many different fields, and its potential for the study of
complex biochemical or chemical mixtures has been widely demonstrated. 2D NMR gives …

Application and methodology of dissolution dynamic nuclear polarization in physical, chemical and biological contexts

S Jannin, JN Dumez, P Giraudeau… - Journal of Magnetic …, 2019 - Elsevier
Dissolution dynamic nuclear polarization (d-DNP) is a versatile method to enhance nuclear
magnetic resonance (NMR) spectroscopy. It boosts signal intensities by four to five orders of …

Brute-force hyperpolarization for NMR and MRI

ML Hirsch, N Kalechofsky, A Belzer… - Journal of the …, 2015 - ACS Publications
Hyperpolarization (HP) of nuclear spins is critical for ultrasensitive nuclear magnetic
resonance (NMR) and magnetic resonance imaging (MRI). We demonstrate an approach …

Low-temperature dynamic nuclear polarization at 9.4 T with a 30 mW microwave source

KR Thurber, WM Yau, R Tycko - Journal of Magnetic Resonance, 2010 - Elsevier
Dynamic nuclear polarization (DNP) can provide large signal enhancements in nuclear
magnetic resonance (NMR) by transfer of polarization from electron spins to nuclear spins …

[HTML][HTML] Optimization of SABRE for polarization of the tuberculosis drugs pyrazinamide and isoniazid

H Zeng, J Xu, J Gillen, MT McMahon, D Artemov… - Journal of magnetic …, 2013 - Elsevier
Hyperpolarization produces nuclear spin polarization that is several orders of magnitude
larger than that achieved at thermal equilibrium thus providing extraordinary contrast and …

Dynamic nuclear polarization opens new perspectives for NMR spectroscopy in analytical chemistry

B Plainchont, P Berruyer, JN Dumez, S Jannin… - 2018 - ACS Publications
Dynamic nuclear polarization (DNP) can boost sensitivity in nuclear magnetic resonance
(NMR) experiments by several orders of magnitude. This Feature illustrates how the …

Rapid sample injection for hyperpolarized NMR spectroscopy

S Bowen, C Hilty - Physical Chemistry Chemical Physics, 2010 - pubs.rsc.org
Due to its ability to enhance the signal of a single NMR scan by several orders of magnitude,
solid-to-liquid state dynamic nuclear polarization (DNP) appears well suited for the analysis …