Abstract Fibroblast growth factor 21 (FGF21) is a stress-inducible hormone that has
important roles in regulating energy balance and glucose and lipid homeostasis through a …

Two types of thermogenic fat cells, brown adipocytes and beige adipocytes, play a key role
in the regulation of systemic energy homeostasis in mammals. Both brown fat and beige fat …

Sarcopenia, an age-associated decline in skeletal muscle mass coupled with functional
deterioration, may be exacerbated by obesity leading to higher disability, frailty, morbidity …

Fibroblast growth factor 21 (FGF21) is a hormone that regulates important metabolic
pathways. FGF21 is expressed in several metabolically active organs and interacts with …

Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several
organs and regulates energy homeostasis. Excitement surrounding this relatively recently …

Mammals have two types of thermogenic adipocytes: brown adipocytes and beige
adipocytes. Thermogenic adipocytes express high levels of uncoupling protein 1 (UCP1) to …

Certain white adipose tissue (WAT) depots are readily able to convert to a “brown-like” state
with prolonged cold exposure or exposure to β-adrenergic compounds. This process is …

Dietary sugars, fructose and glucose, promote hepatic de novo lipogenesis and modify the
effects of a high-fat diet (HFD) on the development of insulin resistance. Here, we show that …

Since its identification in 2000, the interest of scientists in the hepatokine fibroblast growth
factor (FGF) 21 has tremendously grown, and still remains high, due to a wealth of very …

The family of fibroblast growth factors (FGFs) regulates a plethora of developmental
processes, including brain patterning, branching morphogenesis and limb development …