Highlights•Next generation sequencing technologies have enabled large-scale genome
analyses.•Pan-genome analyses provide a framework for predicting and modeling genomic …

With the advance of sequencing technologies, the landscape of genomic analysis has been
transformed, by moving from single strain to species (or even higher taxa)-wide genomic …

Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Gardnerella vaginalis is associated with a spectrum of clinical conditions, suggesting high
degrees of genetic heterogeneity among stains. Seventeen G. vaginalis isolates were …

Background The broad ecological distribution of L. casei makes it an insightful subject for
research on genome evolution and lifestyle adaptation. To explore evolutionary …

Background Infections by pan-drug resistant Acinetobacter baumannii plague military and
civilian healthcare systems. Previous A. baumannii pan-genomic studies used modest …

Microbial community metagenomes and individual microbial genomes are becoming
increasingly accessible by means of high-throughput sequencing. Assessing organismal …

Moraxella catarrhalis is a significant cause of otitis media and exacerbations of chronic
obstructive pulmonary disease. Here, we characterize a phase‐variable DNA …

Moraxella catarrhalis is a human-restricted opportunistic bacterial pathogen of the
respiratory mucosa. It frequently colonizes the nasopharynx asymptomatically, but is also an …

The airway epithelium is the primary site where inhaled and resident microbiota interacts
between themselves and the host, potentially playing an important role on allergic asthma …