AIDS is caused by two lentiviruses: HIV-1 and HIV-2 [1, 2]. AIDS was first recognized in the
1980s and is presently the leading cause of death in developing countries. Globally, it is …

Background Despite significant reductions in mother-to-child HIV-1 transmission risks due to
the advancements and scale-up of antiretroviral therapy (ART), the global burden of HIV-1 …

Background. Emergence of human immunodeficiency virus type 1 (HIV-1) drug resistance
may limit the benefits of antiretroviral therapy in resource-limited settings. The prevalence of …

Treatment of HIV-1 with antiretroviral therapy may select mutations in the pol gene
associated with resistance to reverse transcriptase inhibitors and protease inhibitors. To …

Patients infected with HIV-1 of subtype other than B ('non-subtype B') or with HIV-2 are being
treated with antiretroviral drugs in increasing numbers. In addition, healthcare providers and …

ABSTRACT HIV-1 uses cellular machinery to bud from infected cells. This cellular machinery
is comprised of several multiprotein complexes known as endosomal sorting complexes …

Background. Now that highly active antiretroviral therapy (HAART) is being initiated on a
large scale in West Africa, it remains controversial whether protease inhibitors (PIs) …

Background This work evaluates the role of subtype F human immunodeficiency virus type 1
(HIV-1) protease (PR) substitutions L89M and L90M in viral replication and resistance to PR …

Objective: To evaluate the virological outcomes in children and adolescents infected with
HIV-1 in Salvador, Bahia according to genotyping results. Methods: We retrospectively …

Background. Most published data on antiretroviral-drug resistance is generated from in vitro
or in vivo studies of subtype B virus. However, this subtype is associated with! 10% of HIV …