This review covers the physiological aspects of regulation of the arabinose operon in
Escherichia coli and the physical and regulatory properties of the operon's controlling gene …

To cause the diarrheal disease cholera, Vibrio cholerae must effectively colonize the small
intestine. In order to do so, the bacterium needs to successfully travel through the stomach …

The function of the Vibrio 7 th pandemic island-1 (VSP-1) in cholera pathogenesis has
remained obscure. Utilizing chromatin immunoprecipitation sequencing and RNA …

Cyclic di-and linear oligo-nucleotide signals activate defenses against invasive nucleic
acids in animal immunity; however, their evolutionary antecedents are poorly understood …

Free fatty acids (FFAs) have long been acknowledged for their antimicrobial activity. More
recently, long-chain FFAs (> 12 carbon atoms) are receiving increased attention for their …

Bile acids are prominent host and microbiota metabolites that modulate host immunity and
microbial pathogenesis. However, the mechanisms by which bile acids suppress microbial …

Sensing and responding to environmental changes is essential for bacteria to adapt and
thrive, and nucleotide-derived second messengers are central signaling systems in this …

Vibrio cholerae causes 3 to 5 million cases of cholera annually, resulting in 100,000 to
120,000 deaths (1, 2). Infection occurs through the ingestion of contaminated water or food …

Whole cell biosensors (WCBs) have multiple applications for environmental monitoring,
detecting a wide range of pollutants. WCBs depend critically on the sensitivity and specificity …

To be successful pathogens, bacteria must often restrict the expression of virulence genes to
host environments. This requires a physical or chemical marker of the host environment as …