Force spectroscopy of single cells using atomic force microscopy

A Viljoen, M Mathelié-Guinlet, A Ray… - Nature Reviews …, 2021 - nature.com
Physical forces and mechanical properties have critical roles in cellular function, physiology
and disease. Over the past decade, atomic force microscopy (AFM) techniques have …

[HTML][HTML] How bacterial pathogens colonize their hosts and invade deeper tissues

D Ribet, P Cossart - Microbes and infection, 2015 - Elsevier
Bacterial pathogens have evolved a wide range of strategies to colonize and invade human
organs, despite the presence of multiple host defense mechanisms. In this review, we will …

The MSCRAMM family of cell-wall-anchored surface proteins of gram-positive cocci

TJ Foster - Trends in microbiology, 2019 - cell.com
The microbial surface components recognizing adhesive matrix molecules (MSCRAMMs)
are a family of proteins that are defined by the presence of two adjacent IgG-like folded …

Design of antibacterial surfaces and interfaces: polyelectrolyte multilayers as a multifunctional platform

JA Lichter, KJ Van Vliet, MF Rubner - Macromolecules, 2009 - ACS Publications
The adhesion and proliferation of bacteria on abiotic surfaces pose challenges related to
human infection, including subsequent formation of antibiotic-resistant biofilms in both …

Single-molecule force stability of the SARS-CoV-2–ACE2 interface in variants-of-concern

MS Bauer, S Gruber, A Hausch, MCR Melo… - Nature …, 2024 - nature.com
Mutations in SARS-CoV-2 have shown effective evasion of population immunity and
increased affinity to the cellular receptor angiotensin-converting enzyme 2 (ACE2) …

Rolling cell adhesion

RP McEver, C Zhu - Annual review of cell and developmental …, 2010 - annualreviews.org
Rolling adhesion on vascular surfaces is the first step in recruiting circulating leukocytes,
hematopoietic progenitors, or platelets to specific organs or to sites of infection or injury …

Composition and development of oral bacterial communities

RJ Palmer Jr - Periodontology 2000, 2014 - Wiley Online Library
The oral bacterial microbiome encompasses approximately 700 commonly occurring
phylotypes, approximately half of which can be present at any time in any individual. These …

Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection

K Sharma, N Dhar, VV Thacker, TM Simonet… - Elife, 2021 - elifesciences.org
Uropathogenic Escherichia coli (UPEC) proliferate within superficial bladder umbrella cells
to form intracellular bacterial communities (IBCs) during early stages of urinary tract …

CRIg functions as a macrophage pattern recognition receptor to directly bind and capture blood-borne gram-positive bacteria

Z Zeng, BGJ Surewaard, CHY Wong, JA Geoghegan… - Cell host & …, 2016 - cell.com
Kupffer cells (KCs), the vast pool of intravascular macrophages in the liver, help to clear
blood-borne pathogens. The mechanisms by which KCs capture circulating pathogens …

Staphylococcus aureus clumping factor A is a force-sensitive molecular switch that activates bacterial adhesion

P Herman-Bausier, C Labate… - Proceedings of the …, 2018 - National Acad Sciences
Clumping factor A (ClfA), a cell-wall–anchored protein from Staphylococcus aureus, is a
virulence factor in various infections and facilitates the colonization of protein-coated …