Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression?
JL Bell, K Wächter, B Mühleck, N Pazaitis… - Cellular and molecular …, 2013 - Springer
The insulin-like growth factor-2 mRNA-binding proteins 1, 2, and 3 (IGF2BP1, IGF2BP2,
IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies …
IGF2BP3) belong to a conserved family of RNA-binding, oncofetal proteins. Several studies …
[HTML][HTML] The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer
M Lederer, N Bley, C Schleifer, S Hüttelmaier - Seminars in cancer biology, 2014 - Elsevier
The post-transcriptional control of gene expression mediated by RNA-binding proteins
(RBPs), long non-coding RNAs (lncRNAs) as well as miRNAs is essential to determine …
(RBPs), long non-coding RNAs (lncRNAs) as well as miRNAs is essential to determine …
[HTML][HTML] Proteogenomic characterization of endometrial carcinoma
We undertook a comprehensive proteogenomic characterization of 95 prospectively
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …
collected endometrial carcinomas, comprising 83 endometrioid and 12 serous tumors. This …
High-grade endometrial carcinomas: morphologic and immunohistochemical features, diagnostic challenges and recommendations
This review of challenging diagnostic issues concerning high-grade endometrial carcinomas
is derived from the authors' review of the literature followed by discussions at the …
is derived from the authors' review of the literature followed by discussions at the …
[HTML][HTML] Reproducibility of histological cell type in high-grade endometrial carcinoma
G Han, D Sidhu, MA Duggan, J Arseneau, M Cesari… - Modern pathology, 2013 - Elsevier
Subclassification of endometrial carcinoma according to histological type shows variable
interobserver agreement. The aim of this study was to assess specifically the interobserver …
interobserver agreement. The aim of this study was to assess specifically the interobserver …
Insulin growth factor-2 binding protein 3 (IGF2BP3) is a glioblastoma-specific marker that activates phosphatidylinositol 3-kinase/mitogen-activated protein kinase …
R Suvasini, B Shruti, B Thota, SV Shinde… - Journal of Biological …, 2011 - ASBMB
Glioblastoma is the most common and malignant form of primary astrocytoma. Upon
investigation of the insulin-like growth factor (IGF) pathway, we found the IGF2BP3/IMP3 …
investigation of the insulin-like growth factor (IGF) pathway, we found the IGF2BP3/IMP3 …
Oncofetal protein IMP3, a new cancer biomarker
Y Gong, BA Woda, Z Jiang - Advances in anatomic pathology, 2014 - journals.lww.com
IMP3 is a member of a family of RNA-binding proteins that consists of IMP1, IMP2 and IMP3.
These proteins contain 2 RNA recognition motifs and 4 K-homology domains that allow them …
These proteins contain 2 RNA recognition motifs and 4 K-homology domains that allow them …
Diffuse expression of RNA-binding protein IMP3 predicts high-stage lymph node metastasis and poor prognosis in colorectal adenocarcinoma
RH Yuan, CC Wang, CC Chou, KJ Chang… - Annals of surgical …, 2009 - Springer
Background IMP3 (insulinlike growth factor II mRNA-binding protein 3) is a newly identified
oncofetal RNA-binding protein that is involved in cell growth and cell migration during the …
oncofetal RNA-binding protein that is involved in cell growth and cell migration during the …
RNA m6A methylation regulators in ovarian cancer
J Guo, J Zheng, H Zhang, J Tong - Cancer cell international, 2021 - Springer
Abstract N6-methyladenosine (m6A) is the most abundant RNA modification of mammalian
mRNAs and plays a vital role in many diseases, especially tumours. In recent years, m6A …
mRNAs and plays a vital role in many diseases, especially tumours. In recent years, m6A …
Regulation of IMP3 by EGFR signaling and repression by ERβ: implications for triple-negative breast cancer
S Samanta, VM Sharma, A Khan, AM Mercurio - Oncogene, 2012 - nature.com
Insulin-like growth factor II (IGF-II) mRNA-binding protein 3 (IMP3) is emerging as a useful
indicator of the progression and outcome of several cancers. IMP3 expression is associated …
indicator of the progression and outcome of several cancers. IMP3 expression is associated …