The authors define molecular imaging, according to the Society of Nuclear Medicine and
Molecular Imaging, as the visualization, characterization, and measurement of biological …

Targeted anticancer drugs block cancer cell growth by interfering with specific signaling
pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing …

Glioblastoma (GBM) is the most prevalent malignant primary brain tumour in adults. GBM
typically has a poor prognosis, mainly due to a lack of effective treatment options leading to …

Development of the novel diagnostic and therapeutic approaches in neuro-oncology
requires tumor models that closely reproduce the biological features of patients' tumors …

Today, in preclinical studies, optical bioimaging based on luminescence and fluorescence is
indispensable in studying the development of neoplastic transformations, the proliferative …

Whole‐genome sequencing (WGS) of circulating tumour DNA (ctDNA) is now a clinically
important biomarker for predicting therapy response, disease burden and disease …

Background Glioblastoma is a highly infiltrative, currently incurable brain cancer. To date,
translation of novel therapies for glioblastoma from the laboratory into clinical trials has …

Background Infiltration of glioblastoma (GBM) throughout the brain leads to its inevitable
recurrence following standard-of-care treatments, such as surgical resection, chemo-, and …

Nowadays, molecular imaging technologies have a pivotal role in the field of clinical
oncology. The utilization of imaging methods in the early detection of cancer, assessment of …

IDH wild-type glioblastoma (GBM) is the most prevalent malignant primary brain tumour in
adults. GBM typically has a poor prognosis, mainly due to a lack of effective treatment …