The pathobiology of human fungal infections

GD Brown, ER Ballou, S Bates, EM Bignell… - Nature Reviews …, 2024 - nature.com
Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

One population, multiple lifestyles: commensalism and pathogenesis in the human mycobiome

DM Proctor, RA Drummond, MS Lionakis, JA Segre - Cell host & microbe, 2023 - cell.com
Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

The biological control effect of Bacillus cereus on strawberry leaf spot disease caused by Neopestalotiopsis clavispora

S Zhang, J Wu, J Chen, S Jun, Y Yuan, X Dai… - Scientia …, 2024 - Elsevier
With their distinctive flavor, fragrance, and nutritional value, strawberry (Fragaria× ananassa
Duch.) fruits are popular worldwide. However, strawberry is susceptible to pathogenic fungi …

Metabolic Plasticity and Virulence-Associated Factors of Sporothrix brasiliensis Strains Related to Familiar Outbreaks of Cat-to-Human Transmitted Sporotrichosis

D Corrêa-Junior, IB de Andrade, V Alves… - Journal of Fungi, 2023 - mdpi.com
Sporothrix brasiliensis is the main agent of zoonotic sporotrichosis transmitted by domestic
cats in South America. In humans, sporotrichosis commonly presents with cutaneous or …

Drivers of diversification in fungal pathogen populations

D Murante, DA Hogan - PLoS pathogens, 2024 - journals.plos.org
To manage and treat chronic fungal diseases effectively, we require an improved
understanding of their complexity. There is an increasing appreciation that chronic infection …

Importance of the Aspergillus fumigatus Mismatch Repair Protein Msh6 in Antifungal Resistance Development

J Lucio, I Gonzalez-Jimenez, A Roldan, J Amich… - Journal of Fungi, 2024 - mdpi.com
One of the systems responsible for the recognition and repair of mistakes occurring during
cell replication is the DNA mismatch repair (MMR) system. Two major protein complexes …

Analysis of the bacterial and fungal populations in South African sorghum beer (umqombothi) using full-length 16S rRNA amplicon sequencing

E Hlangwani, A Abrahams, K Masenya… - World Journal of …, 2023 - Springer
There is a need to profile microorganisms which exist pre-and-post-production of
umqombothi, to understand its microbial diversity and the interactions which subsequently …

CbCyp51-Mediated Demethylation Inhibitor Resistance Is Modulated by Codon Bias

LI Rangel, N Wyatt, I Courneya, MB Natwick… - …, 2024 - Am Phytopath Society
Cercospora leaf spot, caused by the fungus Cercospora beticola, is the most destructive
foliar disease of sugarbeet worldwide. Resistance to the sterol demethylation inhibitor (DMI) …

Comparing development of drug resistance by Cryptococcus neoformans to chemically distinct azole anti-fungal compounds

L Burke - 2023 - tigerprints.clemson.edu
Cryptococcus neoformans is a fungus that primarily infects humans who have weakened
immune systems. An azole drug, Fluconazole, is commonly administered against C …