Traditional and scientific evidence attribute numerous bioactivities of Licorice (Glycyrrhiza
glabra Linn.) in aging-related disorders. In this state-of-art review, an extensive search in …

The use of medicinal plants has grown in popularity in recent decades because, as natural
ingredients, they have fewer adverse effects and are more effective than synthetic …

Glycyrrhizin (glycyrrhizic acid), a bioactive triterpenoid saponin constituent of Glycyrrhiza
glabra, is a traditional medicine possessing a plethora of pharmacological anti-inflammatory …

Imperatorin, an active ingredient extracted from Angelica and Qianghuo, has anti-
inflammatory, anti-oxidative stress damage, blocking calcium channels, and other …

Neurological diseases have consistently represented a significant challenge in both clinical
treatment and scientific research. As research has progressed, the significance of …

Individual differences in gut microbiota can affect the pharmacokinetics of drugs.
Yokukansan is a traditional Japanese kampo medicine used to treat peripheral symptoms of …

Purpose Cognitive impairment is one of the main symptoms of Alzheimer disease and other
dementias. Glycyrrhiza uralensis is a natural product that has a protective effect against …

Licorice is a popular sweetener and a thirst quencher in many food products particularly in
Europe and the Middle East and also one of the oldest and most frequently used herbs in …

RESULTS There was a significant decrease in spatial and objective recognition memory in
LPS-induced cognitive impairment group, as measured by the T-maze and novel object …

In silico modeling of blood-brain barrier (BBB) permeability plays an important role in early
discovery of central nervous system (CNS) drugs due to its high-throughput and cost …