Vitamin D and genetic susceptibility to multiple sclerosis

C Scazzone, L Agnello, G Bivona, B Lo Sasso… - Biochemical …, 2021 - Springer
Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system
(CNS), resulting from the interaction among genetic, epigenetic, and environmental factors …

[HTML][HTML] A review of the critical role of vitamin D axis on the immune system

G Daryabor, N Gholijani, FR Kahmini - Experimental and Molecular …, 2023 - Elsevier
In recent years, the physiological and molecular functions of vitamin D (Vit-D) have been
deeply investigated. At first, Vit-D was considered a regulator of mineral and skeletal …

Association between vitamin D receptor (VDR) polymorphisms and the risk of multiple sclerosis (MS): an updated meta-analysis

D Imani, B Razi, M Motallebnezhad, R Rezaei - BMC neurology, 2019 - Springer
Background The association between the Vitamin D Receptor (VDR) gene polymorphism
and the risk of Multiple sclerosis (MS) has been evaluated in several researches. However …

Environmental influencers, microRNA, and multiple sclerosis

EMA Mohammed - Journal of central nervous system …, 2020 - journals.sagepub.com
Multiple sclerosis (MS) is a complex neurological disorder characterized by an aberrant
immune system that affects patients' quality of life. Several environmental factors have …

Exonic variants of genes related to the vitamin D signaling pathway in the families of familial multiple sclerosis using whole‐exome next generation sequencing

V Pytel, JA Matías‐Guiu, L Torre‐Fuentes… - Brain and …, 2019 - Wiley Online Library
Abstract Introduction Vitamin D (VD) deficiency has been associated with multiple sclerosis
(MS) and other autoimmune diseases (AIDs). However, the effect of the genetics of VD on …

Association of vitamin D receptor gene polymorphisms and the risk of multiple sclerosis: a meta analysis

D Zhang, L Wang, R Zhang, S Li - Archives of Medical Research, 2019 - Elsevier
Background Previous studies have reported vitamin D receptor (VDR) polymorphisms in
multiple sclerosis (MS); however, the results remain contradictory. This study aimed to …

Association of vitamin D receptor polymorphisms with vitamin D and calcium levels in Turkish multiple sclerosis patients

A Elkama, G Orhan, B Karahalil - Neurodegenerative Disease …, 2022 - Taylor & Francis
Aim: The present study was conducted to assess the impact of gene (vitamin D receptor
[VDR] polymorphisms)–environment (serum vitamin D and calcium levels) interaction on …

Gene expression profiles of YAP1, TAZ, CRB3, and VDR in familial and sporadic multiple sclerosis among an Iranian population

S Khalilian, Z Hojati, F Dehghanian… - Scientific Reports, 2021 - nature.com
Alterations in the regulatory mechanisms that control the process of myelination in the
nervous system, may lead to the impaired myelination in the Multiple sclerosis. The Hippo …

Vitamin D and the epidemiology of multiple sclerosis

KL Munger, A Ascherio - Feldman and Pike's Vitamin D, 2024 - Elsevier
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous
system, and vitamin D nutrition has been identified as an important risk factor for both MS …

Assessment of vitamin D-binding protein (DBP) gene polymorphisms and their correlation with multiple sclerosis: a case-control study in a sample of the Syrian …

B Alhomsi, G Aboualchamat, I Alkadi - Egyptian Journal of Medical Human …, 2020 - Springer
Background Vitamin D deficiency is a major health concern as it increases the risk of
developing many serious diseases. Recently, the correlation between vitamin D deficiency …