Epstein–barr virus history and pathogenesis

H Yu, ES Robertson - Viruses, 2023 - mdpi.com
Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish
asymptomatic life-long persistence. It is associated with a large spectrum of diseases …

A comprehensive human gastric cancer organoid biobank captures tumor subtype heterogeneity and enables therapeutic screening

HHN Yan, HC Siu, S Law, SL Ho, SSK Yue, WY Tsui… - Cell stem cell, 2018 - cell.com
Gastric cancer displays marked molecular heterogeneity with aggressive behavior and
treatment resistance. Therefore, good in vitro models that encompass unique subtypes are …

EBV and apoptosis: the viral master regulator of cell fate?

L Fitzsimmons, GL Kelly - Viruses, 2017 - mdpi.com
Epstein–Barr virus (EBV) was first discovered in cells from a patient with Burkitt lymphoma
(BL), and is now known to be a contributory factor in 1–2% of all cancers, for which there are …

Single-cell transcriptomic analysis defines the interplay between tumor cells, viral infection, and the microenvironment in nasopharyngeal carcinoma

S Jin, R Li, MY Chen, C Yu, LQ Tang, YM Liu, JP Li… - Cell research, 2020 - nature.com
Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignancy
with a complex tumor ecosystem. How the interplay between tumor cells, EBV, and the …

N (6)‐methyladenosine‐binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay

TL Xia, X Li, X Wang, YJ Zhu, H Zhang, W Cheng… - EMBO …, 2021 - embopress.org
Abstract N 6‐methyladenosine (m6A) modification of mRNA mediates diverse cellular and
viral functions. Infection with Epstein–Barr virus (EBV) is causally associated with …

Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen …

Y Liu, Q Jiang, X Liu, X Lin, ZB Tang, C Liu, J Zhou… - …, 2019 - thelancet.com
Background Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-related tumor.
The role of EBV-encoding miR-BART22 is still unclear in NPC. This study aimed to identify …

Comparative analysis of gammaherpesvirus circular RNA repertoires: conserved and unique viral circular RNAs

NA Ungerleider, V Jain, Y Wang, NJ Maness… - Journal of …, 2019 - Am Soc Microbiol
Recent studies have identified circular RNAs (circRNAs) expressed from the Epstein-Barr
virus (EBV) and Kaposi's sarcoma herpesvirus (KSHV) human DNA tumor viruses. To gain …

Functional implications of Epstein-Barr virus lytic genes in carcinogenesis

LF Yap, AKC Wong, IC Paterson, LS Young - Cancers, 2022 - mdpi.com
Simple Summary Epstein-Barr virus (EBV) was the first human tumor virus to be discovered
and is a causative agent for several cancer types of epithelial and lymphoid origin. EBV has …

[HTML][HTML] Adoptive T-cell therapy for Epstein-Barr virus–related lymphomas

HE Heslop, S Sharma, CM Rooney - Journal of Clinical Oncology, 2021 - ncbi.nlm.nih.gov
Over the last two decades there has been increasing interest in using antigen-specific T
cells expanded in vitro to treat hematologic malignancies. Lymphomas associated with …

Analysis of Epstein-Barr virus genomes and expression profiles in gastric adenocarcinoma

I Borozan, M Zapatka, L Frappier, V Ferretti - Journal of virology, 2018 - Am Soc Microbiol
Epstein-Barr virus (EBV) is a causative agent of a variety of lymphomas, nasopharyngeal
carcinoma (NPC), and∼ 9% of gastric carcinomas (GCs). An important question is whether …