Mechanism and regulation of meiotic recombination initiation

I Lam, S Keeney - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Meiotic recombination involves the formation and repair of programmed DNA double-strand
breaks (DSBs) catalyzed by the conserved Spo11 protein. This review summarizes recent …

The molecular biology of meiosis in plants

R Mercier, C Mézard, E Jenczewski… - Annual review of …, 2015 - annualreviews.org
Meiosis is the cell division that reshuffles genetic information between generations.
Recently, much progress has been made in understanding this process; in particular, the …

DNA damage and repair in plants–from models to crops

V Manova, D Gruszka - Frontiers in plant science, 2015 - frontiersin.org
The genomic integrity of every organism is constantly challenged by endogenous and
exogenous DNA-damaging factors. Mutagenic agents cause reduced stability of plant …

The plant DNA damage response: signaling pathways leading to growth inhibition and putative role in response to stress conditions

MU Nisa, Y Huang, M Benhamed… - Frontiers in plant …, 2019 - frontiersin.org
Maintenance of genome integrity is a key issue for all living organisms. Cells are constantly
exposed to DNA damage due to replication or transcription, cellular metabolic activities …

The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation

T Robert, A Nore, C Brun, C Maffre, B Crimi, V Guichard… - Science, 2016 - science.org
Meiotic recombination is induced by the formation of DNA double-strand breaks (DSBs)
catalyzed by SPO11, the ortholog of subunit A of TopoVI DNA topoisomerase (TopoVIA) …

A DNA topoisomerase VI–like complex initiates meiotic recombination

N Vrielynck, A Chambon, D Vezon, L Pereira… - Science, 2016 - science.org
The SPO11 protein catalyzes the formation of meiotic DNA double strand breaks (DSBs) and
is homologous to the A subunit of an archaeal topoisomerase (topo VI). Topo VI are …

Initiation of meiotic recombination: how and where? Conservation and specificities among eukaryotes

B de Massy - Annual review of genetics, 2013 - annualreviews.org
Meiotic recombination is essential for fertility in most sexually reproducing species. This
process also creates new combinations of alleles and has important consequences for …

Molecular genetic analyses of microsporogenesis and microgametogenesis in flowering plants

H Ma - Annu. Rev. Plant Biol., 2005 - annualreviews.org
In flowering plants, male reproductive development requires the formation of the stamen,
including the differentiation of anther tissues. Within the anther, male meiosis produces …

Mechanisms used by plants to cope with DNA damage

Z Hu, T Cools, L De Veylder - Annual review of plant biology, 2016 - annualreviews.org
Because the genome stores all genetic information required for growth and development, it
is of pivotal importance to maintain DNA integrity, especially during cell division, when the …

Spo11 and the formation of DNA double-strand breaks in meiosis

S Keeney - Recombination and meiosis: crossing-over and …, 2007 - Springer
Meiotic recombination is carried out through a specialized pathway for the formation and
repair of DNA double-strand breaks made by the Spo11 protein, a relative of archaeal …