Anion transport and supramolecular medicinal chemistry

PA Gale, JT Davis, R Quesada - Chemical Society Reviews, 2017 - pubs.rsc.org
New approaches to the transmembrane transport of anions are discussed in this review.
Advances in the design of small molecule anion carriers are reviewed in addition to …

Self‐assembled artificial ion‐channels toward natural selection of functions

S Zheng, L Huang, Z Sun… - Angewandte Chemie …, 2021 - Wiley Online Library
Owing to their significant physiological functions, especially as selective relays for
translocation of physiological relevant species through cellular membranes, natural ion …

An artificial molecular shuttle operates in lipid bilayers for ion transport

S Chen, Y Wang, T Nie, C Bao, C Wang… - Journal of the …, 2018 - ACS Publications
Inspired by natural biomolecular machines, synthetic molecular-level machines have been
proven to perform well-defined mechanical tasks and measurable work. To mimic the …

Anion transport with chalcogen bonds

S Benz, M Macchione, Q Verolet… - Journal of the …, 2016 - ACS Publications
In this report, we introduce synthetic anion transporters that operate with chalcogen bonds.
Electron-deficient dithieno [3, 2-b; 2′, 3′-d] thiophenes (DTTs) are identified as ideal to …

Organic and hybrid molecular systems

VP Ananikov, EA Khokhlova, MP Egorov… - Mendeleev …, 2015 - Elsevier
The design of functional organic and hybrid molecular systems has shown outstanding
recent growth and is a high priority in the development of new technologies and novel …

Pnictogen-bonding catalysis and transport combined: Polyether transporters made in situ

HV Humeniuk, A Gini, X Hao, F Coelho, N Sakai… - JACS Au, 2021 - ACS Publications
The combination of catalysis and transport across lipid bilayer membranes promises
directional access to a solvent-free and structured nanospace that could accelerate …

Formation of supramolecular channels by reversible unwinding-rewinding of bis (indole) double helix via ion coordination

D Mondal, M Ahmad, B Dey, A Mondal… - Nature …, 2022 - nature.com
Stimulus-responsive reversible transformation between two structural conformers is an
essential process in many biological systems. An example of such a process is the …

A glutathione activatable ion channel induces apoptosis in cancer cells by depleting intracellular glutathione levels

JA Malla, RM Umesh, S Yousf, S Mane… - Angewandte Chemie …, 2020 - Wiley Online Library
Cancer cells use elevated glutathione (GSH) levels as an inner line of defense to evade
apoptosis and develop drug resistance. In this study, we describe a novel 2, 4 …

Chloride transport through supramolecular barrel-rosette ion channels: lipophilic control and apoptosis-inducing activity

T Saha, A Gautam, A Mukherjee, M Lahiri… - Journal of the …, 2016 - ACS Publications
Despite the great interest in artificial ion channel design, only a small number of channel-
forming molecules are currently available for addressing challenging problems, particularly …

Challenges in the development of organic and hybrid molecular systems

VP Ananikov, KI Galkin, MP Egorov… - Mendeleev …, 2016 - Elsevier
The rapid development of organic chemistry and catalysis has provided outstanding
chemical tools to build complex molecular architectures that were never possible before. In …