Corneal endothelial cell dysfunction: etiologies and management

S Feizi - Therapeutic advances in ophthalmology, 2018 - journals.sagepub.com
A transparent cornea is essential for the formation of a clear image on the retina. The human
cornea is arranged into well-organized layers, and each layer plays a significant role in …

[HTML][HTML] Approaches for corneal endothelium regenerative medicine

P Catala, G Thuret, H Skottman, JS Mehta… - Progress in retinal and …, 2022 - Elsevier
The state of the art therapy for treating corneal endothelial disease is transplantation.
Advances in the reproducibility and accessibility of surgical techniques are increasing the …

Efficient generation of human embryonic stem cell-derived corneal endothelial cells by directed differentiation

KL McCabe, NJ Kunzevitzky, BP Chiswell, X Xia… - PLoS …, 2015 - journals.plos.org
Aim To generate human embryonic stem cell derived corneal endothelial cells (hESC-
CECs) for transplantation in patients with corneal endothelial dystrophies. Materials and …

Cell-Free Amniotic Fluid and Regenerative Medicine: Current Applications and Future Opportunities

CM Bowen, FS Ditmars, A Gupta, JA Reems, WS Fagg - Biomedicines, 2022 - mdpi.com
Amniotic fluid (AF) provides critical biological and physical support for the developing fetus.
While AF is an excellent source of progenitor cells with regenerative properties, recent …

[HTML][HTML] Retinal microvascular abnormalities in children with type 1 diabetes mellitus without visual impairment or diabetic retinopathy

T Li, Y Jia, S Wang, A Wang, L Gao… - … & visual science, 2019 - tvst.arvojournals.org
Purpose: To study the characteristics and associated factors of retinal microvascular
abnormalities in children with type 1 diabetes mellitus (T1DM) without visual impairment and …

Concise review: an update on the culture of human corneal endothelial cells for transplantation

M Parekh, S Ferrari, C Sheridan… - Stem cells …, 2016 - academic.oup.com
The cornea forms the front window of the eye, enabling the transmission of light to the retina
through a crystalline lens. Many disorders of the cornea lead to partial or total blindness, and …

Translational issues for human corneal endothelial tissue engineering

YQ Soh, GSL Peh, JS Mehta - Journal of tissue engineering …, 2017 - Wiley Online Library
Corneal endothelial disorders collectively represent a significant healthcare burden in most
developed nations, and corneal transplantation is currently the only treatment available for …

Collection and characterization of amniotic fluid from scheduled C-section deliveries

J Pierce, P Jacobson, E Benedetti, E Peterson… - Cell and tissue …, 2016 - Springer
Amniotic fluid (AF) possesses anti-inflammatory, anti-microbial and regenerative properties
that make it attractive for use in clinical applications. The goals of this study were to assess …

New developments in corneal endothelial cell replacement

D Spinozzi, A Miron, M Bruinsma, I Dapena… - Acta …, 2021 - Wiley Online Library
Corneal transplantation is currently the most effective treatment to restore corneal clarity in
patients with endothelial disorders. Endothelial transplantation, either by Descemet …

[HTML][HTML] Potential effect of human platelet lysate on in vitro expansion of human corneal endothelial cells compared with Y-27632 ROCK inhibitor

MA Mishan, S Balagholi, T Chamani… - Journal of Ophthalmic …, 2021 - ncbi.nlm.nih.gov
Purpose Corneal endothelial cell (CEC) therapy can be used as a promising therapeutic
option for patients with various corneal endothelial dysfunctions. In this study, we compared …