Parent-of-origin effects occur when the phenotypic effect of an allele depends on whether it
is inherited from the mother or the father. Several phenomena can cause parent-of-origin …

Epigenetics, the transgenerational transfer of phenotypic characters without modification of
gene sequence, is a burgeoning area of study in many disciplines of biology. However, the …

Quantitative trait locus (QTL) analysis is a statistical method that links two types of
information—phenotypic data (trait measurements) and genotypic data (usually molecular …

DNA methylation has a great potential for understanding the aetiology of common complex
traits such as Type 2 diabetes (T2D). Here we perform genome-wide methylated DNA …

Noncommunicable diseases, including cardiovascular disease, diabetes, chronic respiratory
disease, and cancer, are the leading cause of death in the world. The cost, both monetary …

Understanding the origin of phenotypic variation remains one of the principle challenges of
contemporary biology. Recent genome‐wide association studies have identified association …

Common DNA sequence variants inadequately explain variability in fat mass among
individuals. Abnormal body weights are characteristic of specific imprinted-gene disorders …

Background Imprinted genes show expression from one parental allele only and are
important for development and behaviour. This extreme mode of allelic imbalance has been …

Despite increasing emphasis on the genetic study of quantitative traits, we are still far from
being able to chart a clear picture of their genetic architecture, given an inherent complexity …

Parent-of-origin effects (POE) such as genomic imprinting influence growth and body
composition in livestock, rodents, and humans. Here, we report the results of a genome scan …