Neuroinflammation, crucial in neurological disorders like Alzheimer's disease, multiple
sclerosis, and hepatic encephalopathy, involves complex immune responses. Extracellular …

Introduction Hepatic encephalopathy (HE) is a neuropsychiatric syndrome, in patients with
liver disease, which affects life quality and span. Current treatments are lactulose or …

Extracellular vesicles are released by all cell types and contain proteins, microRNAs,
mRNAs, and other bioactive molecules. Extracellular vesicles play an important role in …

MSCs are used for treatment of inflammatory conditions or for regenerative purposes. MSCs
are complete cells and allogenic transplantation is in principle possible, but mostly …

Patients with liver cirrhosis may show minimal hepatic encephalopathy (MHE) with motor
incoordination and cognitive impairment that reduce life quality and span. Motor …

Gut microbiota perturbation and motor dysfunction have been reported in steatosis patients.
Rats with mild liver damage (MLD) show motor dysfunction mediated by neuroinflammation …

The emerging role of extracellular vesicles (EVs) in central nervous system (CNS) diseases
is gaining significant interest, particularly their applications as diagnostic biomarkers and …

Cirrhotic patients may show minimal hepatic encephalopathy (MHE), with mild cognitive
impairment and motor deficits. Hyperammonemia and inflammation are the main …

Dr. Vicente Felipo, together with his mentors, including Prof. Santiago Grisolía, and very
early in his career, created a non-invasive animal model, rats with chronic …

The targeted drug delivery field is rapidly advancing, focusing on developing biocompatible
nanoparticles that meet rigorous criteria of non‐toxicity, biocompatibility, and efficient …