Role of SIRT1 and AMPK in mesenchymal stem cells differentiation

H Chen, X Liu, H Chen, J Cao, L Zhang, X Hu… - Ageing research …, 2014 - Elsevier
The differentiation capabilities of mesenchymal stem cells (MSCs) compromise with age and
with in vitro passages which could impair the efficacy of cell therapy and tissue engineering …

Metabolic regulation of mesenchymal stem cell in expansion and therapeutic application

Y Liu, T Ma - Biotechnology progress, 2015 - Wiley Online Library
Human mesenchymal or stromal cells (hMSCs) isolated from various adult tissues are
primary candidates in cell therapy and tissue regeneration. Despite promising results in …

[HTML][HTML] In vitro induction of alkaline phosphatase levels predicts in vivo bone forming capacity of human bone marrow stromal cells

HJ Prins, AK Braat, D Gawlitta, WJA Dhert, DA Egan… - Stem cell …, 2014 - Elsevier
One of the applications of bone marrow stromal cells (BMSCs) that are produced by ex vivo
expansion is for use in in vivo bone tissue engineering. Cultured stromal cells are a mixture …

Selenium nanoparticles by moderating oxidative stress promote differentiation of mesenchymal stem cells to osteoblasts

S Fatima, R Alfrayh, M Alrashed… - International Journal …, 2021 - Taylor & Francis
Purpose Redox homeostasis plays an important role in the osteogenic differentiation of
human mesenchymal stem cells (hMSCs) for bone engineering. Oxidative stress (OS) is …

Decreased osteogenesis of adult mesenchymal stem cells by reactive oxygen species under cyclic stretch: a possible mechanism of age related osteoporosis

J Tan, X Xu, Z Tong, Q Yu, Y Lin, W Kuang - Bone research, 2015 - nature.com
Age related defect of the osteogenic differentiation of mesenchymal stem cells (MSCs) plays
a key role in osteoporosis. Mechanical loading is one of the most important physical stimuli …

Dynamic adaptation of mesenchymal stem cell physiology upon exposure to surface micropatterns

NRM Beijer, ZM Nauryzgaliyeva, EM Arteaga… - Scientific reports, 2019 - nature.com
Human mesenchymal stem (hMSCs) are defined as multi-potent colony-forming cells
expressing a specific subset of plasma membrane markers when grown on flat tissue culture …

The mechanism of (+) taxifolin's protective antioxidant effect for• OH-treated bone marrow-derived mesenchymal stem cells

X Li, H Xie, Q Jiang, G Wei, L Lin, C Li, X Ou… - Cellular & Molecular …, 2017 - Springer
The natural dihydroflavonol (+) taxifolin was investigated for its protective effect on Fenton
reagent-treated bone marrow-derived mesenchymal stem cells (bmMSCs). Various …

Revisiting MSC expansion from critical quality attributes to critical culture process parameters

C Martin, E Olmos, ML Collignon, N De Isla… - Process …, 2017 - Elsevier
With over 300 clinical trials registered in 2013 and more than 20,000 hits on the NCBI
database, human multipotent stromal cells (hMSC) are widely used and studied as a model …

Deubiquitinating enzyme USP7 is required for self-renewal and multipotency of human bone marrow-derived mesenchymal stromal cells

YJ Kim, KH Park, KM Lee, YM Chun… - International journal of …, 2022 - mdpi.com
Ubiquitin-specific protease 7 (USP7) is highly expressed in a variety of malignant tumors.
However, the role of USP7 in regulating self-renewal and differentiation of human bone …

Comparison of various techniques for the extraction and determination of antioxidants in plants

P Bajerová, M Adam, T Bajer… - Journal of separation …, 2014 - Wiley Online Library
The following extraction techniques have been used for extracting antioxidants (apigenin,
coumarin, esculetin, umbelliferone, bergapten, quercetin, rutin, scopoletin and xanthotoxin) …