[HTML][HTML] Investigating the dynamic interplay between Cellular Immunity and Tumor cells in the Fight Against Cancer: an updated Comprehensive Review

SA Aghapour, M Torabizadeh, SS Bahreiny… - Iranian Journal of Blood …, 2024 - ijbc.ir
The dynamic interplay between cellular immunity and tumor cells is essential in cancer
advancement and response to therapy. This updated, comprehensive review examines the …

A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control

Y Wang, Y Zhang, K Kim, J Han, D Okin, Z Jiang… - Immunity, 2024 - cell.com
Ligand-dependent transcription factors of the nuclear receptor (NR) family regulate diverse
aspects of metazoan biology, enabling communications between distant organs via small …

An interwoven network of transcription factors, with divergent influences from FoxP3, underlies Treg diversity

K Chowdhary, J Léon, D Ramanan, D Mathis… - bioRxiv, 2023 - biorxiv.org
ABSTRACT FoxP3+ CD4+ regulatory T cells (Tregs), essential for immunologic and
organismal homeostasis, have diverse functions and corresponding gene expression …

IL-2 family cytokines IL-9 and IL-21 differentially regulate innate and adaptive type 2 immunity in asthma

F Bick, CMB Gómez, I Lammens… - Journal of Allergy and …, 2024 - Elsevier
Background Asthma is often accompanied by type 2 immunity rich in IL-4, IL-5, and IL-13
cytokines produced by TH 2 lymphocytes or type 2 innate lymphoid cells (ILC2s). IL-2 family …

Meteorin‐like protein/METRNL/Interleukin‐41 ameliorates atopic dermatitis‐like inflammation

D Huang, X Liu, X Gao, CK Choi, G Giglio, L Farah… - Allergy, 2024 - Wiley Online Library
Background Meteorin‐like protein (METRNL)/Interleukin‐41 (IL‐41) is a novel immune‐
secreted cytokine/myokine involved in several inflammatory diseases. However, how …

[HTML][HTML] Regulatory T cell-derived enkephalin imparts pregnancy-induced analgesia

É Midavaine, BC Moraes, J Benitez, SR Rodriguez… - bioRxiv, 2024 - ncbi.nlm.nih.gov
T cells have emerged as sex-dependent orchestrators of pain chronification but the sexually
dimorphic mechanisms by which T cells control pain sensitivity is not resolved. Here, we …

High-efficiency genomic mapping of chromatin-associated targets with CUT&RUN

TM Firestone, BJ Venters, K Novitzky… - bioRxiv, 2024 - biorxiv.org
The precise regulation of chromatin composition is critical to gene expression and cellular
identity, and thus a key component in development and disease. Robust assays to study …

Sexually dimorphic regulatory T cell-derived enkephalin imparts pregnancy-induced analgesia

E Midavaine, BC Moraes, J Benitez, SR Rodriguez… - bioRxiv, 2024 - biorxiv.org
T cells have emerged as sex-dependent orchestrators of pain chronification but the sexually
dimorphic mechanisms by which T cells control pain sensitivity is not resolved. Here, we …

ZFP36-family RNA-binding proteins in regulatory T cells reinforce immune homeostasis.

M Turner, B Sáenz-Narciso, S Bell, L Matheson… - 2024 - researchsquare.com
RNA binding proteins (RBP) of the ZFP36 family limit the differentiation and effector
functions of CD4 and CD8 T cells, but little is known of their expression or function in …

Deciphering the mechanisms by which FoxP3 regulates treg identity: an analysis of naturally occurring IPEX mutations

J Leon - 2023 - theses.hal.science
The transcription factor (TF) FoxP3 plays a crucial role in the immune system by directing the
development and function of regulatory T cells (Tregs). These cells maintain immune …