Tobacco products present a deadly combination of nicotine addiction and carcinogen
exposure resulting in millions of cancer deaths per year worldwide. A plethora of smokeless …

Background The changing prevalence and patterns of tobacco use, the advent of novel
nicotine delivery devices, and the development of new biomarkers prompted an update of …

The tobacco-specific N-nitrosamines 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone
(NNK) and N′-nitrosonornicotine (NNN) always occur together and exclusively in tobacco …

Since 2009, the FDA Center for Tobacco Products (CTP) has had the authority to regulate
the manufacturing, distribution, and marketing of tobacco products in order to reduce the …

The health hazards of smoking are well recognised and recently knowledge about the
harmful effects of nicotine and snus is accumulating. We investigated the factors increasing …

Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …

Objective Smokeless tobacco use is a public health issue throughout the world, but reviews
and analyses of circulatory disease risks associated with smokeless tobacco use may be …

Introduction This study examined changes in biomarkers of exposure (BoE) after 5 days of
nicotine-salt pod system (NSPS) use, compared with continuation of usual-cigarette smoking …

Background: The increasing popularity of non-cigarette nicotine products, especially among
youth, highlights the need for greater attention to their potential risks, including nicotine …

Background: The dose–response relationships between number of cigarettes smoked per
day (CPD) and health outcomes, such as cancer and heart disease, are well established …