Natural compounds in glioblastoma therapy: Preclinical insights, mechanistic pathways, and outlook

K Zhai, M Siddiqui, B Abdellatif, A Liskova, P Kubatka… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is a tumor of the brain or spinal cord with poor clinical
prognosis. Current interventions, such as chemotherapy and surgical tumor resection, are …

DNA damage response and repair in the development and treatment of brain tumors

PM Dana, F Sadoughi, H Mirzaei, Z Asemi… - European Journal of …, 2022 - Elsevier
DNA damage response (DDR) comprising DNA repair and cell-cycle checkpoint pathways,
is considered as a protective process that maintains the integrity of the genome. However …

Effective treatment of a BRAF V600E-mutant epithelioid glioblastoma patient by vemurafenib: a case report

Z Lin, H Xu, R Yang, Z Li, H Zheng, Z Zhang… - Anti-Cancer …, 2022 - journals.lww.com
Epithelioid glioblastoma (E-GBM) is a recently described variant of glioblastoma (GBM)
which is associated with short survival and now added as a provisional entity to WHO 2016 …

Discovery of the first ataxia telangiectasia and Rad3-related (ATR) degraders for cancer treatment

L Huang, J Shao, W Lai, H Gu, J Yang, S Shi… - European Journal of …, 2024 - Elsevier
The first examples of ataxia telangiectasia and Rad3-related (ATR) PROTACs were
designed and synthesized. Among them, the most potent degrader, ZS-7, demonstrated …

Exploring the Bioactive Potential of Pisolithus (Basidiomycota): Comprehensive Insights into Antimicrobial, Anticancer, and Antioxidant Properties for Innovative …

RS Oliveira, M Preto, G Santos, AM Silva… - Microorganisms, 2024 - mdpi.com
Addressing pressing health concerns, modern medical research seeks to identify new
antimicrobials to combat drug resistance, novel molecules for cancer treatment, and …

[HTML][HTML] Short-and long-term efficacy of sustained-release chemotherapy in tumor bed interstitium combined with surgical resection for recurrent malignant glioma

L Wang, Z Wang, Z Liang, G Li, S Duan… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Objective: To discuss and analyze the short-and long-term curative effect of sustained-
release chemotherapy combined with surgical resection on recurrent malignant glioma …