Of men in mice: the development and application of a humanized gnotobiotic mouse model for microbiome therapeutics

JC Park, SH Im - Experimental & molecular medicine, 2020 - nature.com
Considerable evidence points to the critical role of the gut microbiota in physiology and
disease. The administration of live microbes as a therapeutic modality is increasingly being …

The role of intestinal microbiota in cardiovascular disease

M Jin, Z Qian, J Yin, W Xu… - Journal of cellular and …, 2019 - Wiley Online Library
Accumulating evidence has indicated that intestinal microbiota is involved in the
development of various human diseases, including cardiovascular diseases (CVDs). In the …

Cellular and molecular basis of thyroid autoimmunity

J Bogusławska, M Godlewska, E Gajda… - European thyroid …, 2022 - etj.bioscientifica.com
Autoimmune thyroid disease (AITD) is the most common human autoimmune disease. The
two major clinical manifestations of AITD are Graves' disease (GD) and Hashimoto's …

Microbiota and thyroid interaction in health and disease

E Fröhlich, R Wahl - Trends in Endocrinology & Metabolism, 2019 - cell.com
The microbiota has been identified as an important factor in health and in a variety of
diseases. An altered microbiota composition increases the prevalence of Hashimoto's …

The gut microbiota and its interactions with cardiovascular disease

H Xu, X Wang, W Feng, Q Liu, S Zhou… - Microbial …, 2020 - Wiley Online Library
The intestine is colonized by a considerable community of microorganisms that cohabits
within the host and plays a critical role in maintaining host homeostasis. Recently …

Alterations of the gut microbiota in patients with severe chronic heart failure

W Sun, D Du, T Fu, Y Han, P Li, H Ju - Frontiers in microbiology, 2022 - frontiersin.org
Chronic heart failure (CHF) is the final outcome of almost all forms of cardiovascular
diseases, remaining the main cause of mortality worldwide. Accumulating evidence is …

The relationships between the gut microbiota and its metabolites with thyroid diseases

W Jiang, G Lu, D Gao, Z Lv, D Li - Frontiers in endocrinology, 2022 - frontiersin.org
Emerging studies have provided a preliminary understanding of the thyroid-gut axis,
indicating that intestinal microbiota and its metabolites may act directly or indirectly on the …

Graves' disease

TF Davies, S Andersen, R Latif, Y Nagayama… - Nature reviews Disease …, 2020 - nature.com
Graves' disease (GD) is an autoimmune disease that primarily affects the thyroid gland. It is
the most common cause of hyperthyroidism and occurs at all ages but especially in women …

Gut microbiome associated with Graves disease and Graves orbitopathy: the INDIGO multicenter European study

F Biscarini, G Masetti, I Muller… - The Journal of …, 2023 - academic.oup.com
Context Gut bacteria can influence host immune responses but little is known about their
role in tolerance-loss mechanisms in Graves disease (GD; hyperthyroidism caused by …

A randomised controlled study shows supplementation of overweight and obese adults with lactobacilli and bifidobacteria reduces bodyweight and improves well …

DR Michael, AA Jack, G Masetti, TS Davies… - Scientific reports, 2020 - nature.com
In an exploratory, block-randomised, parallel, double-blind, single-centre, placebo-
controlled superiority study (ISRCTN12562026, funded by Cultech Ltd), 220 Bulgarian …