Drug tolerant persister cell plasticity in cancer: A revolutionary strategy for more effective anticancer therapies
J He, Z Qiu, J Fan, X Xie, Q Sheng, X Sui - Signal transduction and …, 2024 - nature.com
Non-genetic mechanisms have recently emerged as important drivers of anticancer drug
resistance. Among these, the drug tolerant persister (DTP) cell phenotype is attracting more …
resistance. Among these, the drug tolerant persister (DTP) cell phenotype is attracting more …
FGFR3 alterations in bladder cancer: Sensitivity and resistance to targeted therapies
M Noeraparast, K Krajina, R Pichler… - Cancer …, 2024 - Wiley Online Library
In this review, we revisit the pivotal role of fibroblast growth factor receptor 3 (FGFR3) in
bladder cancer (BLCA), underscoring its prevalence in both non‐muscle‐invasive and …
bladder cancer (BLCA), underscoring its prevalence in both non‐muscle‐invasive and …
Genomic and transcriptomic profiling of high-risk bladder cancer reveals diverse molecular and microenvironment ecosystems
K Meghani, Y Yu, N Frydenlund, EZ Li, B Choy… - bioRxiv, 2024 - biorxiv.org
Despite surgical resection, rigorous endoscopic surveillance, and immunotherapy with the
Bacillus Calmette-Guerin (BCG) vaccine, 30% of high-risk bladder cancers recur, and 10 …
Bacillus Calmette-Guerin (BCG) vaccine, 30% of high-risk bladder cancers recur, and 10 …
Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor-adapted non-small cell lung cancer cell lines
T Nanthaprakash, C Gourlay, I Oehme, MD Garrett… - bioRxiv, 2024 - biorxiv.org
Here, we introduce sublines of the EGFR-mutant non-small cell lung cancer (NSCLC) cell
lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib …
lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib …
Ribosomal Biogenesis Hyperactivation and ErbB signalling Mediated Network Rewiring Causes Adaptive Resistance to FGFR2 Inhibition
Abstract Fibroblast Growth Factor Receptor 2 inhibition presents a promising therapeutic
approach for restraining the growth and survival of cancer cells, particularly in breast …
approach for restraining the growth and survival of cancer cells, particularly in breast …