Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

The excessive formation of reactive oxygen species (ROS) and impairment of defensive
antioxidant systems leads to a condition known as oxidative stress. The main source of free …

Promising results have been obtained using cerium (Ce) oxide nanoparticles (CNPs) as
antioxidants in biological systems. CNPs have unique regenerative properties owing to their …

Modulation of endogenous cellular defense mechanisms represents an innovative approach
to therapeutic intervention in diseases causing chronic tissue damage, such as in …

The lungs are directly exposed to higher oxygen concentrations than most other tissues.
Increased oxidative stress is a significant part of the pathogenesis of obstructive lung …

Throughout the last 2 decades, experimental evidence from in vitro studies and preclinical
models of disease has demonstrated that reactive oxygen and nitrogen species, including …

Gentamicin is an antibiotic effective against Gram-negative infection, whose clinical use is
limited by its nephrotoxicity. Oxygen free radicals are considered to be important mediators …

Neutrophils play essential roles in several inflammatory reactions. Oxidant/antioxidant
imbalance is thought to be partially involved in the pathogenesis of the disorders. Under the …

This review describes production and effects of reactive oxygen species (ROS) on airway
function. ROS are important in many physiological processes but can also have detrimental …

Understanding mechanisms of aging and determinants of life span will help to reduce age-
related morbidity and facilitate healthy aging. Average lifespan has increased over the last …