Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …

Objective Cannabis sativa is a recreational drug commonly consumed in Europe and is
getting popularity for both recreational and therapeutic use. In some individuals, the use of …

A convergence of evidence shows that use of Cannabis sativa is associated with increased
risk of developing psychotic disorders, including schizophrenia, and earlier age at which …

Cannabis is one of the most commonly used and abused illicit drugs in the world today. The
United States (US) currently has the highest annual prevalence rate of cannabis …

Background Neither environmental nor genetic factors are sufficient to predict the
transdiagnostic expression of psychosis. Therefore, analysis of gene-environment …

Synthetic cannabinoids (SC) are psychoactive drugs that generally produce more severe
clinical outcomes compared to Δ9-tetrahydrocannabinol. This study aimed to evaluate the …

Cannabinoids and the Brain: The Effects of Endogenous and Exogenous Cannabinoids on
Brain Systems and Function - ScienceDirect Skip to main contentSkip to article Elsevier logo …

Abstract Objective COMT rs4680 (Val158Met) genotype moderates the effect of cannabis on
the age of onset of psychosis (AoP). We investigated the association between rs4680 and …

The catechol‐O‐methyltransferase (COMT) gene is thought to have an important role in the
etiopathogenesis of schizophrenia, but there are conflicting results regarding its role in …

Alors que plusieurs États américains ont fait le choix d'assouplir la législation entourant
l'usage récréatif du cannabis et qu'au Canada, cette substance est encadrée par un …