The emerging importance of lymphatics in health and disease: an NIH workshop report

BJ Mehrara, AJ Radtke, GJ Randolph… - The Journal of …, 2023 - Am Soc Clin Investig
The lymphatic system (LS) is composed of lymphoid organs and a network of vessels that
transport interstitial fluid, antigens, lipids, cholesterol, immune cells, and other materials in …

Lymphatic vasculature in ovarian cancer

S Pal, S Bhowmick, A Sharma… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Ovarian cancer (OVCA) is the second most common gynecological cancer and one of the
leading causes of cancer related mortality among women. Recent studies suggest that …

Modeling lymphangiogenesis: Pairing in vitro and in vivo metrics

AC Suarez, JH Hammel, JM Munson - Microcirculation, 2023 - Wiley Online Library
Lymphangiogenesis is the mechanism by which the lymphatic system develops and
expands new vessels facilitating fluid drainage and immune cell trafficking. Models to study …

Role of the renal lymphatic system in heart failure

HM Salah, J Biegus, M Fudim - Current Heart Failure Reports, 2023 - Springer
Abstract Purpose of Review The lymphatic system plays a major but overlooked role in
maintaining fluid homeostasis. Given the unique fluid homeostasis functions of the kidneys …

Imaging of Perirenal and Intrarenal Lymphatic Vessels: Anatomy-Based Approach

H Takahashi, A Inoue, T Tanaka, Y Sato… - Radiographics, 2024 - pubs.rsna.org
The lymphatic system (or lymphatics) consists of lymphoid organs and lymphatic vessels.
Despite the numerous previously published studies describing conditions related to …

The role of lymphangiogenesis in cardiovascular diseases and heart transplantation

RC Ji - Heart Failure Reviews, 2022 - Springer
Cardiac lymphangiogenesis plays an important physiological role in the regulation of
interstitial fluid homeostasis, inflammatory, and immune responses. Impaired or excessive …

Lymphangiogenesis and lymphatic barrier dysfunction in renal fibrosis

J Liu, C Yu - International Journal of Molecular Sciences, 2022 - mdpi.com
As an integral part of the vascular system, the lymphatic vasculature is essential for tissue
fluid homeostasis, nutritional lipid assimilation and immune regulation. The composition of …

[HTML][HTML] CD137L-macrophage induce lymphatic endothelial cells autophagy to promote lymphangiogenesis in renal fibrosis

H Wei, L Chen, Q Li, X Liang, K Wang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Renal lymphangiogenesis is a new field of international nephrology in recent years and
plays an important role in the progression of chronic renal disease. CD137 was originally …

Abnormal lymphatic sphingosine-1-phosphate signaling aggravates lymphatic dysfunction and tissue inflammation

D Kim, W Tian, TTH Wu, M Xiang, R Vinh, JL Chang… - Circulation, 2023 - Am Heart Assoc
BACKGROUND: Lymphedema is a global health problem with no effective drug treatment.
Enhanced T-cell immunity and abnormal lymphatic endothelial cell (LEC) signaling are …

Immune landscape and the key role of APOE+ monocytes of lupus nephritis under the single‐cell and spatial transcriptional vista

Y Tang, Y Zhang, X Li, R Xu, Y Ji, J Liu… - Clinical and …, 2023 - Wiley Online Library
Background Lupus nephritis (LN) is among the most common complication of systemic lupus
erythematosus (SLE) with high mortality and morbidity. The analysis of LN kidney's local …