While most tissues exhibit their greatest growth during development, adipose tissue is
capable of additional massive expansion in adults. Adipose tissue expandability is …

Abstract Development of the retinal vasculature is based on highly coordinated signalling
between different cell types of the retina, integrating internal metabolic requirements with …

The Neuropilins (Nrps) are a family of essential cell surface receptors involved in multiple
fundamental cellular signaling cascades. Nrp family members have key functions in VEGF …

Background: Pathological angiogenesis is the hallmark of many vision-threatening
diseases. Anti-VEGF is a primary treatment with substantial beneficial effects. However, such …

Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the retina and a leading
cause of visual impairment and childhood blindness worldwide. The disease is …

The understanding, diagnosis, and treatment of retinopathy of prematurity have changed in
the 70 years since the original description of retrolental fibroplasia associated with high …

Retinopathy of prematurity (ROP) is an important cause of childhood blindness globally, and
the incidence is rising. The disease is characterized by initial arrested retinal vascularization …

Cell-cell communication is pivotal to guide embryo development, as well as to maintain adult
tissues homeostasis and control immune response. Among extracellular factors responsible …

In the central nervous system, endothelial cells (ECs) and pericytes (PCs) of blood vessel
walls cooperatively form a physical and chemical barrier to maintain neural homeostasis …

Transient global ischemia selectively damages neurons in specific brain areas. A
reproducible pattern of selective vulnerability is observed in the dorsal hippocampus of …