Boron neutron capture therapy: Current status and future perspectives

MA Dymova, SY Taskaev, VA Richter… - Cancer …, 2020 - Wiley Online Library
The development of new accelerators has given a new impetus to the development of new
drugs and treatment technologies using boron neutron capture therapy (BNCT). We …

Boron delivery agents for neutron capture therapy of cancer

RF Barth, P Mi, W Yang - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the
nuclear capture and fission reactions that occur when the stable isotope, boron-10, is …

Boron neutron capture therapy (BNCT): A unique role in radiotherapy with a view to entering the accelerator-based BNCT era

M Suzuki - International journal of clinical oncology, 2020 - Springer
Boron neutron capture therapy (BNCT) has a unique property of tumor-cell-selective heavy-
particle irradiation. BNCT can form large dose gradients between cancer cells and normal …

A realistic appraisal of boron neutron capture therapy as a cancer treatment modality

RF Barth, Z Zhang, T Liu - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary therapeutic modality based on the nuclear
capture and fission reactions that occur when the stable isotope boron-10 is irradiated with …

L-Type amino acid transporter 1 as a target for drug delivery

E Puris, M Gynther, S Auriola, KM Huttunen - Pharmaceutical research, 2020 - Springer
Our growing understanding of membrane transporters and their substrate specificity has
opened a new avenue in the field of targeted drug delivery. The L-type amino acid …

Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer

RF Barth, MG H Vicente, OK Harling, WS Kiger… - Radiation …, 2012 - Springer
Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on
the nuclear capture and fission reactions that occur when non-radioactive boron-10, which is …

A critical review of radiation therapy: from particle beam therapy (proton, carbon, and BNCT) to beyond

Y Matsumoto, N Fukumitsu, H Ishikawa… - Journal of personalized …, 2021 - mdpi.com
In this paper, we discuss the role of particle therapy—a novel radiation therapy (RT) that has
shown rapid progress and widespread use in recent years—in multidisciplinary treatment …

The basis and advances in clinical application of boron neutron capture therapy

H He, J Li, P Jiang, S Tian, H Wang, R Fan, J Liu… - Radiation …, 2021 - Springer
Boron neutron capture therapy (BNCT) was first proposed as early as 1936, and research on
BNCT has progressed relatively slowly but steadily. BNCT is a potentially useful tool for …

Boron neutron capture therapy for malignant brain tumors

SI Miyatake, S Kawabata, R Hiramatsu… - Neurologia medico …, 2016 - jstage.jst.go.jp
Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on
the nuclear capture and fission reactions that occur when non-radioactive boron-10, which is …

Therapeutic nucleus-access BNCT drug combined CD47-targeting gene editing in glioblastoma

J Chen, Q Dai, QY Yang, X Bao, Y Zhou… - Journal of …, 2022 - Springer
Glioblastoma is the most common brain primary malignant tumor with the highest mortality.
Boron neutron capture therapy (BNCT) can efficiently kill cancer cells on the cellular scale …