Approximately 40% of treatments of chronic and recurrent osteomyelitis fail in part due to
bacterial persistence. Staphylococcus aureus, the predominant pathogen in human …

Staphylococcus aureus is an opportunistic human pathogen, which is a leading cause of
infections worldwide. The challenge in treating S. aureus infection is linked to the …

Bacterial persister cells are phenotypic variants that exhibit a transient non-growing state
and antibiotic tolerance. Here, we provide in vitro evidence of Staphylococcus aureus …

Bone infection is a devastating disease characterized by recurrence, drug-resistance, and
high morbidity, that has prompted clinicians and scientists to develop novel approaches to …

Abstract Background The opportunistic pathogen Staphylococcus aureus is an
asymptomatically carried member of the microbiome of about one third of the human …

Methicillin-resistant Staphylococcus aureus (MRSA) infections pose a global health threat,
especially with the continuous development of antibiotic resistance. As an opportunistic …

Healthcare-associated infections (HAIs) represent a burden for public health with a high
prevalence and high death rates associated with them. Pathogens with a high potential for …

Staphylococcus aureus is internalised by host cells in vivo, and recent research results
suggest that the bacteria use this intracellularity to persist in the host and form a reservoir for …

Bone and joint infections are devastating afflictions. Although medical interventions and
advents have improved their care, bone and joint infections still portend dismal outcomes …

The phagocytic cells of the innate immune system are an essential first line of antimicrobial
defense, and yet Candida albicans, one of the most problematic fungal pathogens, is …