Plant derived active compounds of ayurvedic neurological formulation, Saraswatharishta as a potential dual leucine zipper kinase inhibitor: an in-silico study
Recent findings have highlighted the essential role of dual leucine zipper kinase (DLK) in
neuronal degeneration. Saraswatharishta (SWRT), an ayurvedic formulation utilized in …
neuronal degeneration. Saraswatharishta (SWRT), an ayurvedic formulation utilized in …
Exploring the binding effects of natural products and antihypertensive drugs on SARS-CoV-2: an in silico investigation of main protease and spike protein
K Moschovou, M Antoniou, E Chontzopoulou… - International Journal of …, 2023 - mdpi.com
In this in silico study, we conducted an in-depth exploration of the potential of natural
products and antihypertensive molecules that could serve as inhibitors targeting the key …
products and antihypertensive molecules that could serve as inhibitors targeting the key …
4 ″-Alkyl EGCG Derivatives Induce Cytoprotective Autophagy Response by Inhibiting EGFR in Glioblastoma Cells
Epidermal growth factor receptor (EGFR)-targeted therapy has been proven vital in the last
two decades for the treatment of multiple cancer types, including nonsmall cell lung cancer …
two decades for the treatment of multiple cancer types, including nonsmall cell lung cancer …
[HTML][HTML] Identification of potential antiviral lead inhibitors against SARS-CoV-2 Main protease: structure-guided virtual screening, docking, ADME, and MD simulation …
G Lanka, R Bathula, B Ghosh, SR Potlapally - Artificial Intelligence …, 2023 - Elsevier
The novel coronavirus disease (COVID-19) was caused by a new strain of the virus SARS-
CoV-2 in December 2019 emerged as deadly pandemic that affected millions of people …
CoV-2 in December 2019 emerged as deadly pandemic that affected millions of people …
Predicting immune response targets in orthoflaviviruses through sequence homology and computational analysis
Context Flaviviruses cause severe encephalitic or hemorrhagic diseases in humans. Its
members, Kyasanur forest disease virus (KFDV) and Alkhumra hemorrhagic fever virus …
members, Kyasanur forest disease virus (KFDV) and Alkhumra hemorrhagic fever virus …
Stereo-selectivity of enantiomeric inhibitors to ubiquitin-specific protease 7 (USP7) dissected by molecular docking, molecular dynamics simulations, and binding free …
Y Zhang, W Dou, Z Zhao, G Li, C Li, X Chen, L Mou - Molecular Diversity, 2024 - Springer
The ubiquitin-specific protease 7 (USP7), as a member of deubiquitination enzymes,
represents an attractive therapeutic target for various cancers, including prostate cancer and …
represents an attractive therapeutic target for various cancers, including prostate cancer and …
Exploring antiviral properties of Favipiravir analogues; A computational approach
TV Thomas, AKS Pillai, A Thakur - AIP Conference Proceedings, 2024 - pubs.aip.org
The role of repurposed and analogous drug systems has become prominent during the
pandemic when the world struggled to synthesize and mobilize novel antiviral medicines in …
pandemic when the world struggled to synthesize and mobilize novel antiviral medicines in …