The catalytic asymmetric electrophilic functionalization of the less reactive N-heteroaromatic
compounds has been reported using the approach of the introduction of an exocyclic amino …

Modern times have witnessed an uprise in the synthesis and derivatization of nitrogen-
containing fused heterocycles. Amination reactions involving nitrene chemistry have always …

Efficacious protocols have been established to synthesize a structurally privileged Π-
extended coumarin-fused pyridone nucleus by activating the vinylic C (sp2)–H bond of …

A ruthenium-catalyzed oxidative coupling of vinylene carbonate with isoxazoles has been
developed to achieve the direct C–H formylmethylation of a diverse array of arylisoxazoles …

A straightforward, rapid, green, and efficient synthetic procedure has been introduced for
easy access to the synthetically highly substituted arylideneisoxazol-5-(4 H)-one products. A …

A unique and efficient copper catalytic system has been established to synthesize
fluorinated 2-azadienes from isoxazoles and CF3-N-tosylhydrazones via crosscoupling …

This work describes the synthesis, characterization, and in vitro and in silico evaluation of
the biological activity of new functionalized isoxazole derivatives. The structures of all new …

Photocatalyst-free visible light-enabled direct oxygenation of furan-tethered α-azidoketones
was studied. The reaction yielded various products depending on the substituents, with …

Many methods report the scission of N–O bonds of aromatic heterocycles and their
subsequent functionalization. Oxidative addition is one of the presumed pathways through …

A ring-opening fluorination of isoxazoles has been developed. Upon treatment of isoxazoles
with an electrophilic fluorinating agent (Selectfluor), fluorination followed by deprotonation …