Morphine exhibits important pharmacological effects for which it has been used in medical
practice for quite a long time. However, it has a high addictive potential and can be abused …

Emerging evidence shows that redox‐sensitive signal transduction pathways are critical for
developmental processes, including proliferation, differentiation, and apoptosis. As a …

Morphine, a commonly used antinociceptive drug in hospitals, is known to cross the blood-
brain barrier (BBB) by first passing through brain endothelial cells. Despite its pain-relieving …

This paper is the 29th consecutive installment of the annual review of research concerning
the endogenous opioid system, now spanning 30 years of research. It summarizes papers …

Aim: Substance abuse has become a universal crisis in our modern age. Among illegal
substances, opium and its derivatives have been ranked second in terms of usage after …

Oxidative stress resulting from reactive oxygen species (ROS) is known to play a key role in
numerous neurological disorders, including neuropathic pain. Morphine is one of the …

In this paper, the enzymatic detoxification of aflatoxin B1 (AFB1) by laccase was studied, and
the prooxidant properties and mutagenicity of the detoxification products were compared …

Morphine has been widely used for pain management. Other than analgesia, it has effects
on vascular endothelial cells, including angiogenesis and apoptosis. An in vitro model of …

This study was carried out to investigate the protective role of taurine (2-
aminoethanesulphonicacid) against morphine-induced neurotoxicity in C6 cells. It was …

Opioids and their receptors have received remarkable attention because they have the
ability to alter immune function, which affects disease progression. In vitro and in vivo …