Energy-driven genome regulation by ATP-dependent chromatin remodellers

S Eustermann, AB Patel, KP Hopfner, Y He… - … Reviews Molecular Cell …, 2024 - nature.com
The packaging of DNA into chromatin in eukaryotes regulates gene transcription, DNA
replication and DNA repair. ATP-dependent chromatin remodelling enzymes (re) arrange …

[HTML][HTML] Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes

GJ Narlikar, R Sundaramoorthy, T Owen-Hughes - Cell, 2013 - cell.com
Chromatin provides both a means to accommodate a large amount of genetic material in a
small space and a means to package the same genetic material in different chromatin states …

In vitro reconstitution of chromatin domains shows a role for nucleosome positioning in 3D genome organization

E Oberbeckmann, K Quililan, P Cramer… - Nature Genetics, 2024 - nature.com
Eukaryotic genomes are organized into chromatin domains. The molecular mechanisms
driving the formation of these domains are difficult to dissect in vivo and remain poorly …

A high-resolution protein architecture of the budding yeast genome

MJ Rossi, PK Kuntala, WKM Lai, N Yamada, N Badjatia… - Nature, 2021 - nature.com
The genome-wide architecture of chromatin-associated proteins that maintains chromosome
integrity and gene regulation is not well defined. Here we use chromatin …

Determinants of nucleosome positioning

K Struhl, E Segal - Nature structural & molecular biology, 2013 - nature.com
Nucleosome positioning is critical for gene expression and most DNA-related processes.
Here we review the dominant patterns of nucleosome positioning that have been observed …

Nutritional control of growth and development in yeast

JR Broach - Genetics, 2012 - academic.oup.com
Availability of key nutrients, such as sugars, amino acids, and nitrogen compounds, dictates
the developmental programs and the growth rates of yeast cells. A number of overlapping …

Genomic nucleosome organization reconstituted with pure proteins

N Krietenstein, M Wal, S Watanabe, B Park… - Cell, 2016 - cell.com
Chromatin remodelers regulate genes by organizing nucleosomes around promoters, but
their individual contributions are obfuscated by the complex in vivo milieu of factor …

Recurrent neural network for predicting transcription factor binding sites

Z Shen, W Bao, DS Huang - Scientific reports, 2018 - nature.com
It is well known that DNA sequence contains a certain amount of transcription factors (TF)
binding sites, and only part of them are identified through biological experiments. However …

Origins of specificity in protein-DNA recognition

R Rohs, X Jin, SM West, R Joshi… - Annual review of …, 2010 - annualreviews.org
Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

[HTML][HTML] Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution

HS Rhee, BF Pugh - Cell, 2011 - cell.com
Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins
bind throughout a genome. However, DNA contamination and DNA fragmentation …