Role of neuropeptides in anxiety, stress, and depression: from animals to humans

V Kormos, B Gaszner - Neuropeptides, 2013 - Elsevier
Major depression, with its strikingly high prevalence, is the most common cause of disability
in communities of Western type, according to data of the World Health Organization. Stress …

Corticotropin releasing factor: a key role in the neurobiology of addiction

EP Zorrilla, ML Logrip, GF Koob - Frontiers in neuroendocrinology, 2014 - Elsevier
Drug addiction is a chronically relapsing disorder characterized by loss of control over intake
and dysregulation of stress-related brain emotional systems. Since the discovery by Wylie …

Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets

RL Hauger, V Risbrough, O Brauns… - CNS & Neurological …, 2006 - ingentaconnect.com
Corticotropin-releasing factor (CRF) and the related urocortin peptides mediate behavioral,
cognitive, autonomic, neuroendocrine and immunologic responses to aversive stimuli by …

Corticotropin-releasing factor receptors and stress-related alterations of gut motor function

Y Taché, B Bonaz - The Journal of clinical investigation, 2007 - Am Soc Clin Investig
Over the past few decades, corticotropin-releasing factor (CRF) signaling pathways have
been shown to be the main coordinators of the endocrine, behavioral, and immune …

The CRF family of neuropeptides and their receptors-mediators of the central stress response

N Dedic, A Chen, JM Deussing - Current molecular …, 2018 - ingentaconnect.com
Background: Dysregulated stress neurocircuits, caused by genetic and/or environmental
changes, underlie the development of many neuropsychiatric disorders. Corticotropin …

Brain and gut CRF signaling: biological actions and role in the gastrointestinal tract

Y Tache, M Larauche, PQ Yuan… - Current molecular …, 2018 - ingentaconnect.com
Background: Corticotropin-releasing factor (CRF) pathways coordinate behavioral,
endocrine, autonomic and visceral responses to stress. Convergent anatomical, molecular …

Peptidergic and functional delineation of the Edinger-Westphal nucleus

MF Priest, SN Freda, IJ Rieth, D Badong… - Cell reports, 2023 - cell.com
Many neuronal populations that release fast-acting excitatory and inhibitory
neurotransmitters in the brain also contain slower-acting neuropeptides. These facultative …

The Edinger‐Westphal nucleus: A historical, structural, and functional perspective on a dichotomous terminology

T Kozicz, JC Bittencourt, PJ May… - Journal of …, 2011 - Wiley Online Library
The eponymous term nucleus of Edinger‐Westphal (EW) has come to be used to describe
two juxtaposed and somewhat intermingled cell groups of the midbrain that differ …

Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs

ÉM Fekete, EP Zorrilla - Frontiers in neuroendocrinology, 2007 - Elsevier
Urocortins, three paralogs of the stress-related peptide corticotropin-releasing factor (CRF)
found in bony fish, amphibians, birds, and mammals, have unique phylogenies …

Localization of nesfatin-1 neurons in the mouse brain and functional implication

M Goebel-Stengel, L Wang, A Stengel, Y Taché - Brain research, 2011 - Elsevier
Nesfatin-1 reduces food intake when injected centrally in rodents. We recently described
wide distribution of nucleobindin2 (NUCB2)/nesfatin-1 immunoreactivity in rat brain …