Analytical techniques for characterization of cyclodextrin complexes in the solid state: A review

P Mura - Journal of pharmaceutical and biomedical analysis, 2015 - Elsevier
Cyclodextrins are cyclic oligosaccharides able to form inclusion complexes with a variety of
hydrophobic guest molecules, positively modifying their physicochemical properties. A …

Differential scanning calorimetry: An invaluable tool for a detailed thermodynamic characterization of macromolecules and their interactions

MH Chiu, EJ Prenner - Journal of Pharmacy and Bioallied …, 2011 - journals.lww.com
Abstract Differential Scanning Calorimetry (DSC) is a highly sensitive technique to study the
thermotropic properties of many different biological macromolecules and extracts. Since its …

Role of thermodynamic, molecular, and kinetic factors in crystallization from the amorphous state

C Bhugra, MJ Pikal - Journal of pharmaceutical sciences, 2008 - Elsevier
Though there is an advantage in using the higher solubility amorphous state in cases where
low solubility limits absorption, physical instability poses a significant barrier limiting its use …

Cannabidiol aqueous solubility enhancement: Comparison of three amorphous formulations strategies using different type of polymers

N Koch, O Jennotte, Y Gasparrini… - International Journal of …, 2020 - Elsevier
Poor aqueous solubility of terpenophenolic compound Cannabidiol (CBD) is a major issue
in the widespread use of this promising therapeutic polyphenol. Moreover, choosing the …

Cyclodextrin as a magic switch in covalent and non-covalent anticancer drug release systems

B Tian, Y Liu, J Liu - Carbohydrate polymers, 2020 - Elsevier
Cancer has been a threat to human health, so its treatment is a huge challenge to the
present medical field. One of commonly used methods is the controlled release of anticancer …

The investigation of binary and ternary sulfobutylether-β-cyclodextrin inclusion complexes with asiaticoside in solution and in solid state

HMSH Soe, S Chamni, P Mahalapbutr… - Carbohydrate …, 2020 - Elsevier
Asiaticoside (AS) is poorly water-soluble compound that can lead to low the bioavailability.
The aims of this study were to determine the cyclodextrin (CD) solubilization of AS and …

Development of Fenofibrate/Randomly Methylated β-Cyclodextrin-Loaded Eudragit® RL 100 Nanoparticles for Ocular Delivery

SY Khin, HMSH Soe, C Chansriniyom… - Molecules, 2022 - mdpi.com
Fenofibrate (FE) has been shown to markedly reduce the progression of diabetic retinopathy
and age-related macular degeneration in clinical trials and animal models. Owing to the …

Amorphous stabilization of BCS II drugs using mesoporous silica

B Tu, S Jonnalagadda - International Journal of Pharmaceutics, 2024 - Elsevier
This study aimed to investigate the amorphous stabilization of BCS Class II drugs using
mesoporous silica as a carrier to produce amorphous solid dispersions. Ibuprofen …

Host–guest interaction study of resveratrol with natural and modified cyclodextrins

V Bertacche, N Lorenzi, D Nava, E Pini… - Journal of inclusion …, 2006 - Springer
The aim of this work is to increase the stability and water solubility of resveratrol by
complexation with different cyclodextrins. Furthermore, physical–chemical properties of each …

Tomato oil encapsulation by α-, β-, and γ-Cyclodextrins: A comparative study on the formation of supramolecular structures, antioxidant activity, and carotenoid stability

M Durante, F Milano, M De Caroli, L Giotta, G Piro… - Foods, 2020 - mdpi.com
Cyclodextrins (CDs) are oligosaccharides, comprising 6 (α), 7 (β), or 8 (γ) glucose residues,
used to prepare oil-in-water emulsions and improve oil stability towards degradation. In this …