Cells release adenosine triphosphate (ATP), which activates plasma membrane–localized
P2X and P2Y receptors and thereby modulates cellular function in an autocrine or paracrine …

The charge of this invited review is to present a convincing case for the fact that cells release
their ATP for physiological reasons. Many of our “purinergic” colleagues as well as …

We show theoretically how adenosine 5′-triphosphate (ATP)-induced dynamic
dissociations of spectrin filaments (from each other and from the membrane) in the …

Corneal transparency is dependent on regulation of the hydration of the corneal stroma.
Water is driven into the cornea across the epithelial and endothelial cell layers by the …

Cystic fibrosis is a frequent autosomal recessive disorder that is caused by the
malfunctioning of a small chloride channel, the cystic fibrosis transmembrane conductance …

ATP is rapidly released from osteoblasts in response to mechanical load. We examined the
mechanisms involved in this release and established that shear‐induced ATP release was …

RBCs are known to release ATP, which acts as a signaling molecule to cause dilation of
blood vessels. A reduction in the release of ATP from RBCs has been linked to diseases …

In close interaction with photoreceptors, the retinal pigment epithelium (RPE) plays an
essential role for visual function. The analysis of RPE functions, specifically ion channel …

Nucleotides within the airway surface liquid (ASL) regulate airway epithelial ion transport
rates by Ca 2+-and protein kinase C-dependent mechanisms via activation of specific P2Y …

In human airways, extracellular adenosine regulates epithelial functions supporting
mucociliary clearance, an important airway defense mechanism against bacterial infection …