Burns and other traumatic injuries represent a substantial biomedical burden. The current
standard of care for deep injuries is autologous split-thickness skin grafting (STSG), which …

Regenerative medicine and tissue engineering aim to promote functional rebuilding of
damaged tissue. Comprehensively profiling cell identity, function and interaction in healthy …

Rationale: Elevated shear stress (ESS) induces vascular remodeling in veins exposed to
arterial blood flow, which can lead to arteriovenous (AV) fistula failure. The molecular …

Diabetic kidney disease (DKD) is characterized by histological changes including fibrosis
and inflammation. Evidence supports that DKD is mediated by the innate immune system …

We previously found IQ motif containing GTPase activating protein (IQGAP1) to be
consistently elevated in lung fibroblasts (LF) isolated from patients with scleroderma …

Background: The introduction of mesh for reinforcement of ventral hernia repair (VHR) led to
a significant reduction in hernia recurrence rates. However, it remains controversial whether …

Soft implantable devices are crucial to optimizing form and function for many patients.
However, periprosthetic capsule fibrosis is one of the major challenges limiting the use of …