Single-cell transcriptome analysis of the in vivo response to viral infection in the cave nectar bat Eonycteris spelaea

AM Gamage, WOY Chan, F Zhu, YT Lim, S Long… - Immunity, 2022 - cell.com
Bats are reservoir hosts of many zoonotic viruses with pandemic potential. We utilized single-
cell transcriptome sequencing (scRNA-seq) to analyze the immune response in bat lungs …

Applications of VirScan to broad serological profiling of bat reservoirs for emerging zoonoses

EC Ruhs, WN Chia, R Foo, AJ Peel, Y Li… - Frontiers in Public …, 2023 - frontiersin.org
Introduction Bats are important providers of ecosystem services such as pollination, seed
dispersal, and insect control but also act as natural reservoirs for virulent zoonotic viruses …

Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host–pathogen interactions in the bat …

LLY Chan, AM Gamage, CW Tan, KS Tan… - Emerging Microbes & …, 2023 - Taylor & Francis
Bats are reservoir hosts for various zoonotic viruses with pandemdic potential in humans
and livestock. In vitro systems for studying bat host–pathogen interactions are of significant …

[HTML][HTML] Application of a bespoke monoclonal antibody panel to characterize immune cell populations in cave nectar bats

S Chen, WR Sia, LJW Tang, AM Gamage, WOY Chan… - Cell reports, 2024 - cell.com
Among their many unique biological features, bats are increasingly recognized as a key
reservoir of many emerging viruses that cause massive morbidity and mortality in humans …

Regulatory T cell-like response to SARS-CoV-2 in Jamaican fruit bats (Artibeus jamaicensis) transduced with human ACE2

B Burke, SM Rocha, S Zhan, M Eckley… - PLoS …, 2023 - journals.plos.org
Insectivorous Old World horseshoe bats (Rhinolophus spp.) are the likely source of the
ancestral SARS-CoV-2 prior to its spillover into humans and causing the COVID-19 …

Genomic Characterization of a Relative of Mumps Virus in Lesser Dawn Bats of Southeast Asia

AC Paskey, XF Lim, JHJ Ng, GK Rice, WN Chia… - Viruses, 2023 - mdpi.com
The importance of genomic surveillance on emerging diseases continues to be highlighted
with the ongoing SARS-CoV-2 pandemic. Here, we present an analysis of a new bat-borne …

[PDF][PDF] Regulatory T Cell-like Response to SARS-CoV-2 in Jamaican Fruit Bats Transduced with Human ACE2

B Burke, SM Rocha, S Zhan, M Eckley, C Reasoner… - researchgate.net
Abstract Insectivorous Old World horseshoe bats (Rhinolophus spp.) are the likely source of
the ancestral SARS-CoV-2 prior to its spillover into humans and causing the COVID-19 …