Antimicrobial peptides of the genus Bacillus: a new era for antibiotics

CD Sumi, BW Yang, IC Yeo… - Canadian journal of …, 2015 - cdnsciencepub.com
The rapid onset of resistance reduces the efficacy of most conventional antimicrobial drugs
and is a general cause of concern for human well-being. Thus, there is great demand for a …

Antifungal peptides: To be or not to be membrane active

M Rautenbach, AM Troskie, JA Vosloo - Biochimie, 2016 - Elsevier
Most antifungal peptides (AFPs), if not all, have membrane activity, while some also have
alternative targets. Fungal membranes share many characteristics with mammalian …

[HTML][HTML] Challenges of drug-resistant malaria

S Sinha, B Medhi, R Sehgal - Parasite, 2014 - ncbi.nlm.nih.gov
Over the past six decades, the drug resistance of Plasmodium falciparum has become an
issue of utmost concern. Despite the remarkable progress that has been made in recent …

The multifaceted antibacterial mechanisms of the pioneering peptide antibiotics tyrocidine and gramicidin S

M Wenzel, M Rautenbach, JA Vosloo, T Siersma… - MBio, 2018 - Am Soc Microbiol
Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S
were the first commercially used antibiotics, yet it remains unclear exactly how they kill …

Antimicrobial peptide action on parasites

M Torrent, D Pulido, L Rivas, D Andreu - Current drug targets, 2012 - ingentaconnect.com
Diseases caused by protozoan parasites can pose a severe thread to human health and are
behind some serious neglected tropical diseases like malaria and leishmaniasis. Though …

Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics

T Mogi, K Kita - Cellular and molecular life sciences, 2009 - Springer
Gramicidin S and polymyxins are small cationic cyclic peptides and act as potent antibiotics
against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial …

[图书][B] Antimalarial natural products

DGI Kingston, MB Cassera - 2022 - Springer
Natural products have made a crucial and unique contribution to human health, and this is
especially true in the case of malaria, where the natural products quinine and artemisinin …

Bacillus spp.; perspectiva de su efecto biocontrolador mediante antibiosis en cultivos afectados por fitopatógenos

C Layton - Nova, 2011 - revistas.unicolmayor.edu.co
El presente estudio documental evalúa el efecto biocontrolador del género Bacillus sp
contra hongos fitopatógenos de plantas, particularmente, a través de relaciones …

Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion

I Lāce, ER Cotroneo, N Hesselbarth… - Journal of Peptide …, 2023 - Wiley Online Library
Membranes consisting of phospholipid bilayers are an essential constituent of eukaryotic
cells and their compartments. The alteration of their composition, structure, and morphology …

Synergistic activity of the tyrocidines, antimicrobial cyclodecapeptides from Bacillus aneurinolyticus, with amphotericin B and caspofungin against Candida albicans …

AM Troskie, M Rautenbach, N Delattin… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Tyrocidines are cationic cyclodecapeptides from Bacillus aneurinolyticus that are
characterized by potent antibacterial and antimalarial activities. In this study, we show that …