Bacteriophages (phages), as natural antibacterial agents, are being rediscovered because
of the growing threat of multi-and pan-drug-resistant bacterial pathogens globally. However …

Initially described a century ago by William Twort and Felix d'Herelle, bacteriophages are
bacterial viruses found ubiquitously in nature, located wherever their host cells are present …

Antibiotic treatments have detrimental effects on the microbiome and lead to antibiotic
resistance. To develop a phage therapy against a diverse range of clinically relevant …

Bacteriophages provide excellent tools for diagnostics, remediation, and targeted
microbiome manipulation, yet isolating viruses with suitable host specificity remains …

Bacteriophages are the most abundant biological entity on earth, acting as the predators
and evolutionary drivers of bacteria. Owing to their inherent ability to specifically infect and …

Highlights•Phages use structurally diverse receptor binding proteins (RBPs) to target
different cell wall structures.•RBPs play a critical role in spatial and temporal positioning of …

The archaeal tailed viruses (arTV), evolutionarily related to tailed double-stranded DNA
(dsDNA) bacteriophages of the class Caudoviricetes, represent the most common isolates …

Anaplastic lymphoma kinase (ALK) and the related leukocyte tyrosine kinase (LTK) are
recently deorphanized receptor tyrosine kinases. Together with their activating cytokines …

The proto-oncogene ALK encodes anaplastic lymphoma kinase, a receptor tyrosine kinase
that is expressed primarily in the developing nervous system. After development, ALK …

The aim of this study was to gain further insight into the diversity of Escherichia coli phages
followed by enhanced work on taxonomic issues in that field. Therefore, we present the …