Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …

This review is focused on several psychiatric disorders in which cognitive impairment is a
major component of the disease, influencing life quality. There are plenty of data proving that …

Translocase of outer mitochondrial membrane 40 (TOMM40) is located in the outer
membrane of mitochondria. TOMM40 is essential for protein import into mitochondria …

As the prevalence of dementia and Alzheimer's disease (AD) increases worldwide, it is
imperative to reflect on the major clinical trials in the prevention of dementia and the …

Transcriptome-wide association studies (TWAS) have been widely used to integrate
transcriptomic and genetic data to study complex human diseases. Within a test dataset …

Alzheimer's disease (AD) is a complex neurological disorder characterized by accumulation
of amyloid plaques and neurofibrillary tangles. Long term investigation of AD pathogenesis …

Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
neurodegeneration and cognitive decline. Evodiamine, a main component in Chinese …

There is limited evidence on the effects of intrauterine chromium (Cr) exposure on children's
cognitive developmental delay (CDD). Further, little is known about the genetic factors in …

Both the APOE ε4 and TOMM40 rs10524523 (“523”) genes have been associated with risk
for Alzheimer's disease (AD) and neuroimaging biomarkers of AD. No studies have …

Abstract Introduction Inherited mitochondrial DNA (mtDNA) variants may influence
Alzheimer's disease (AD) risk. Methods We sequenced mtDNA from 146 AD and 265 …