Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …

Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Age-related macular degeneration (AMD), a degenerative disease in the central macula
area of the neuroretina and the supporting retinal pigment epithelium, is the most common …

Altered metabolic patterns in tumor cells not only meet their own growth requirements but
also shape an immunosuppressive microenvironment through multiple mechanisms …

Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the
adult population worldwide and represent a severe economic burden and public health …

Aging-related diseases (ARDs) are a major global health concern, and the development of
effective therapies is urgently needed. Kaempferol, a flavonoid found in several plants, has …

Aims: Extracellular vesicles (EVs) are membrane-derived vesicles that mediate intercellular
communications. Neutrophils produce different subtypes of EVs during inflammatory …

Melanoma is responsible for most skin cancer-associated deaths globally. The progression
of melanoma is influenced by a number of pathogenic processes. Understanding the …

Landmark genetic studies have revealed the effect of complement biology and its regulation
on the pathogenesis of age-related macular degeneration (AMD). Limited phase 3 clinical …

Ageing decreases the function of the immune system and increases susceptibility to some
chronic, infectious, and autoimmune diseases. Senescence cells, which produce …