COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

The multifaceted roles of NLRP3-modulating proteins in virus infection

J Harris, NA Borg - Frontiers in immunology, 2022 - frontiersin.org
The innate immune response to viruses is critical for the correct establishment of protective
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …

Design of type-3 fuzzy systems and ensemble neural networks for COVID-19 time series prediction using a firefly algorithm

P Melin, D Sánchez, JR Castro, O Castillo - Axioms, 2022 - mdpi.com
In this work, information on COVID-19 confirmed cases is utilized as a dataset to perform
time series predictions. We propose the design of ensemble neural networks (ENNs) and …

European Network for ICU-Related Respiratory Infections (ENIRRIs): a multinational, prospective, cohort study of nosocomial LRTI

I Martin-Loeches, LF Reyes, S Nseir, O Ranzani… - Intensive care …, 2023 - Springer
Purpose Lower respiratory tract infections (LRTI) are the most frequent infectious
complication in patients admitted to the intensive care unit (ICU). We aim to report the …

Clinical characteristics, systemic complications, and in-hospital outcomes for patients with COVID-19 in Latin America. LIVEN-Covid-19 study: A prospective …

LF Reyes, A Bastidas, PO Narváez, D Parra-Tanoux… - PloS one, 2022 - journals.plos.org
Purpose The COVID-19 pandemic has spread worldwide, and almost 396 million people
have been infected around the globe. Latin American countries have been deeply affected …

Early steroids and ventilator-associated pneumonia in COVID-19-related ARDS

P Lamouche-Wilquin, J Souchard, M Pere, M Raymond… - Critical Care, 2022 - Springer
Rationale Early corticosteroid treatment is used to treat COVID-19-related acute respiratory
distress syndrome (ARDS). Infection is a well-documented adverse effect of corticosteroid …

Respiratory support in patients with severe COVID-19 in the International Severe Acute Respiratory and Emerging Infection (ISARIC) COVID-19 study: a prospective …

LF Reyes, S Murthy, E Garcia-Gallo, L Merson… - Critical care, 2022 - Springer
Background Up to 30% of hospitalised patients with COVID-19 require advanced respiratory
support, including high-flow nasal cannulas (HFNC), non-invasive mechanical ventilation …

Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective …

LF Reyes, A Rodriguez, YV Fuentes, S Duque… - Scientific reports, 2023 - nature.com
Around one-third of patients diagnosed with COVID-19 develop a severe illness that
requires admission to the Intensive Care Unit (ICU). In clinical practice, clinicians have …

Les misérables: a Parallel Between Antimicrobial Resistance and COVID-19 in Underdeveloped and Developing Countries

G Pérez Jorge, IC Rodrigues dos Santos Goes… - Current infectious …, 2022 - Springer
Abstract Purpose of Review The COVID-19 pandemic has been responsible for more than
6.3 million deaths worldwide. During the pandemic, the indiscriminate use of antibiotics has …

[HTML][HTML] Glucocorticoid therapy for acute respiratory distress syndrome: Current concepts

Y Zhao, Z Yao, S Xu, L Yao, Z Yu - Journal of Intensive Medicine, 2024 - Elsevier
Acute respiratory distress syndrome (ARDS), a fatal critical disease, is induced by various
insults. ARDS represents a major global public health burden, and the management of …