Whole-genome sequencing of bacteria has recently emerged as a cost-effective and
convenient approach for addressing many microbiological questions. Here, we review the …

Salmonella enterica infections are common causes of bloodstream infection in low-resource
areas, where they may be difficult to distinguish from other febrile illnesses and may be …

Background: The Global Typhoid Genomics Consortium was established to bring together
the typhoid research community to aggregate and analyse Salmonella enterica serovar …

The emergence of multidrug-resistant (MDR) typhoid is a major global health threat affecting
many countries where the disease is endemic. Here whole-genome sequence analysis of …

It is well established that multidrug-resistance efflux pumps encoded by bacteria can confer
clinically relevant resistance to antibiotics. It is now understood that these efflux pumps also …

Efflux pump genes and proteins are present in both antibiotic-susceptible and antibiotic-
resistant bacteria. Pumps may be specific for one substrate or may transport a range of …

Nontyphoidal Salmonella are important foodborne pathogens that cause gastroenteritis,
bacteremia, and subsequent focal infection. These hardy bacteria are especially problematic …

The global problem of antimicrobial resistance is particularly pressing in developing
countries, where the infectious disease burden is high and cost constraints prevent the …

Multiple drug (antibiotic) resistance (MDR) has become a major threat to the treatment of
typhoid and other infectious diseases. Since the 1970s, this threat has increased in …

OBJECTIVE: To inform policy-makers about introduction of preventive interventions against
typhoid, including vaccination. METHODS: A population-based prospective surveillance …