Nitrate levels in our water resources have increased in many areas of the world largely due
to applications of inorganic fertilizer and animal manure in agricultural areas. The regulatory …

Delayed cerebral ischemia is a major predictor of poor outcomes in patients who suffer
subarachnoid hemorrhage. Treatment options are limited and often ineffective despite many …

Nitric oxide (NO), the smallest signalling molecule known, is produced by three isoforms of
NO synthase (NOS; EC 1.14. 13.39). They all utilize l-arginine and molecular oxygen as …

At high concentrations, free radicals and radical-derived, nonradical reactive species are
hazardous for living organisms and damage all major cellular constituents. At moderate …

Nitric oxide (NO) released by vascular endothelial cells accounts for the relaxation of strips
of vascular tissue1 and for the inhibition of platelet aggregation2 and platelet adhesion3 …

Hydrogen sulfide (H2S), which is well known as a toxic gas, is produced endogenously in
mammalian tissues from L-cysteine mainly by two pyridoxal-5′-phosphate-dependent …

ContextThe efficient sequestration of hemoglobin by the red blood cell membrane and the
presence of multiple hemoglobin clearance mechanisms suggest a critical need to prevent …

Physiological blood flow induces the secretion of vasoactive compounds, notably nitric
oxide, and promotes endothelial cell elongation and reorientation parallel to the direction of …

Nitric Oxide Donors: Chemical Activities and Biological Applications | Chemical Reviews ACS
ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Systemic arterial hypertension is a highly prevalent cardiovascular risk factor that causes
significant morbidity and mortality, and is becoming an increasingly common health problem …